Newsletter
Best Papers in General Surgery
The five that matter, every day.
A multimodal artificial intelligence model demonstrated impressive results for hepatocellular carcinoma (HCC) detection. Evaluations from 1,092 participants across training, internal validation, and external validation cohorts showed the model's area under the curve (AUC) values reaching 0.985 and 0.915. Notably, it excelled in identifying small HCCs…
A multidisciplinary framework successfully identified 85 genes linked to panoptosis in intrahepatic cholangiocarcinoma (ICC) patients. Researchers developed a panoptosis risk score (panrs) model with five critical hub genes, demonstrating high efficacy in prognosis prediction across diverse cohorts. The study also highlighted macrophage roles in the…
A meta-analysis involving 1,244 patients found that hepatic arterial infusion chemotherapy (HAIC) combined with lenvatinib and PD-1 inhibitors significantly improved overall survival (OS) and progression-free survival (PFS) compared to lenvatinib with PD-1 inhibitors alone. Specifically, this combination led to a hazard ratio of 2.11 for…
Standardizing nursing processes for abdominal drainage in cholelithiasis patients significantly improves recovery outcomes. A retrospective study involving 264 patients revealed that those treated with standardized protocols reported substantially less postoperative pain, greater activity levels within 24 hours, and reduced leakage incidents compared to those who…
Endoscopic ultrasonography (EUS) with novel scopes and ultrasound systems proves effective for diagnosing pancreaticobiliary diseases, evidenced by a 100% success rate in interventional procedures. Although shear wave velocity (SWV) showed no significant differences among various pancreatic conditions, variations in effective SWV were noted. The advanced…
A meta-analysis of 17 studies involving over 3 million patients reveals heightened venous thromboembolism (VTE) rates among postoperative individuals who were COVID-19 positive. Notably, those undergoing total joint arthroplasty, other orthopedic surgery, and emergency general surgery experienced significantly elevated VTE rates compared to their COVID-19…
A study involving 305 patients found that delayed coloanal anastomosis (dcaa) resulted in a significantly lower overall postoperative complication rate of 15% compared to 31% for immediate coloanal anastomosis (icaa). Early and late anastomosis-related complications were also reduced in the dcaa group. Furthermore, at two…
Integrating biophysical modeling and machine learning significantly improves intraoperative assessment of intestinal perfusion in laparoscopic low anterior rectal resection. An analysis of 68 patients demonstrated that the automated model outperformed traditional scoring methods, achieving a root mean square error of 2.47 and a mean absolute…
A systematic review analyzing 2.3 million procedures from 72,000 surgeons reveals a U-shaped relationship between surgeon age and surgical complications. High-volume surgeons maintained stable outcomes up to age 70, while low-volume surgeons faced significant complications after age 55. Complex procedures showed more pronounced age effects…
A comprehensive geriatric assessment combined with individualized prehabilitation programs may significantly reduce unplanned hospital readmissions in older adults after digestive surgery. The study emphasizes the importance of addressing underlying frailty, comorbidities, and postoperative complications. By coordinating efforts between surgical teams and geriatric specialists, improved perioperative…
