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Best Papers in General Surgery
The five that matter, every day.
A comparative analysis of 203 pancreatic cancer patients between 2010-2015 and 2016-2021 revealed significant improvements in outcomes due to multidisciplinary treatment. Patients in the latter group had higher preoperative chemotherapy rates (95%) and lower morbidity and pancreatic fistula rates. Overall survival notably improved, from 26.0…
A study identifies critical contextual factors for effective implementation of enhanced recovery programs (ERPs) in hospitals. Out of 86 hospitals, 30.2% achieved high ERP adherence. Success scenarios included low-socioeconomic status hospitals eager for change lacking team cohesion, low surgical volume hospitals with strong staff buy-in,…
Neoadjuvant chemotherapy using gemcitabine and S-1 significantly outperforms upfront surgery for patients with resectable pancreatic ductal adenocarcinoma (PDAC). In a randomized trial with 364 participants, median overall survival was 37.0 months for the chemotherapy group compared to 26.6 months for the surgery group, with a…
The systematic review reveals that implementing shared decision-making (SDM) in gastrointestinal cancer care faces challenges despite its importance for patient autonomy. Researchers synthesized data from 37 qualitative studies, identifying nine influencing factors categorized into two subthemes. Key strategies include enhancing medical staff's understanding of patients'…
An artificial intelligence model employing endoscopic ultrasonography (EUS) has demonstrated effective differentiation between small gastric stromal tumors (GSTs) and gastric leiomyomas (GLs). Utilizing a dataset of 358 EUS images, the ResNet50 architecture achieved impressive area under the curve (AUC) values of 0.994 and 0.911 for…
In a study investigating treatment options for unresectable intrahepatic cholangiocarcinoma (ICCA), idarubicin exhibited the highest cytotoxicity among ten tested drugs, greatly outperforming the standard gemcitabine and cisplatin combination. Tumor growth was significantly inhibited in mouse models treated with idarubicin and gemcis, with pronounced effects particularly…
Carbohydrate antigen 19-9 (CA19-9) evaluation through a novel method significantly predicts overall and disease-free survival in borderline resectable pancreatic adenocarcinoma patients undergoing neoadjuvant therapy. A study with 991 participants revealed that those with a mean Δf below defined thresholds demonstrated significantly improved prognoses, associating with…
A retrospective analysis of 120 ventral hernia repairs highlights the advantages of robotic-assisted techniques over laparoscopic methods. The robotic group demonstrated significantly higher mean hernia defects, shorter operating times, fewer postoperative complications, reduced pain scores at 24 hours and 14 days post-surgery, and better patient…
In laparoscopic enhanced totally extra-peritoneal inguinal hernia repairs, balloon trocar dissection outperforms optical trocar entry by significantly shortening surgery duration (62 vs. 75 min, p
A prognostic study developed validated pre- and post-operative nomograms predicting disease-free survival (DFS) in patients who underwent curative resection for right-sided colon cancer. In a cohort of 822 patients, 1-, 3-, and 5-year DFS rates were found to be 85.6%, 72.5%, and 57.6%, respectively. Key…
