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Best Papers in General Surgery
The five that matter, every day.
A dynamic tool utilizing albumin-bilirubin (ALBI) scores and fibrosis-4 (FIB-4) index trends improves risk stratification for patients undergoing hepatocellular carcinoma resection. K-means clustering revealed three patient groups with varying complication risks. Those in the lowest ALBI cluster had a 76% reduced odds of severe complications…
An analysis of 260,009 acute pancreatitis patients in England from 2013 to 2023 reveals an incidence rate rising by 2.6% annually, with 456 cases per million. In-hospital mortality stands at 4.5%, while the 10-year survival rate reaches 63.9%. Factors influencing better long-term outcomes include biliary…
A prospective multicenter study evaluated the effectiveness of endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) in diagnosing autoimmune pancreatitis (AIP) using the International Consensus Diagnostic Criteria (ICDC). Results showed that EUS-FNB improved diagnostic levels in 92.3% of suspected AIP patients, with a diagnostic accuracy of 94.2%. The…
Preventive strategies have been shown to lower the risk of postoperative delirium (POD) by 49% after intraabdominal surgery, according to a systematic review and meta-analysis of 16 randomized controlled trials involving 4,060 participants. The findings underscore the necessity for standardized screening and intervention protocols to…
A recent study demonstrated that a machine learning-based model significantly improves the differentiation between non-neoplastic and neoplastic gallbladder polyps. Analyzing data from 744 patients, the combined model achieved an AUC of 0.910, compared to lower scores from individual models, thus reducing unnecessary cholecystectomies. Notably, the…
A Belgian registry of 1342 liver resections found that minimally invasive liver surgery (MILS) was preferred in 51% of cases. MILS patients had better short-term outcomes compared to open surgery, including shorter surgery times, less blood loss, and lower complication rates. Notably, centers performing more…
A higher neutrophil percentage-to-albumin ratio (npar) significantly predicts conservative treatment failure in acute cholecystitis, with an optimal cutoff of 21.5 showing 88.8% sensitivity and 84.8% specificity. In a cohort of 508 patients, 21.1% experienced failed treatment, leading to interventions like emergency surgery and drainage. Npar…
Conversion rates during minimally invasive left pancreatectomy (MILP) reached 15.6% in a study of 2,104 patients across 55 centers. Key risk factors included male sex, BMI over 25 kg/m², a history of laparotomy, initial pancreatitis, and larger tumor size. A conversion risk score (CRS) was…
An expert panel's re-evaluation of colorectal liver metastases led to a notable increase in treatment eligibility. Initially, only 29% of patients were deemed resectable before systemic treatment, but this figure rose to 68% following multiple assessments. Alarmingly, nearly 29% of patients recognized as resectable were…
Analysis of 3006 patients across six clinical trials demonstrates that the Japan Clinical Oncology Group postoperative complication (JCOG PC) criteria show a high agreement with the Common Terminology Criteria for Adverse Events (CTCAE). The median agreement was 99.5% for early complications and 99.4% for late…
