Newsletter
Best Papers in General Surgery
The five that matter, every day.
A machine learning-based predictive model has been developed to estimate the incidence of endoscopic retrograde cholangiopancreatography (ERCP) after emergency laparoscopic cholecystectomy. Analyzing data from 8,854 patients, the model revealed a postoperative ERCP incidence of 5.7% in training and 6.4% in testing datasets. The gradient-boosting decision…
A meta-analysis of 20 studies involving 1,719 patients revealed that exercise-based prehabilitation significantly reduced overall postoperative complications with a risk ratio of 0.74. While it did not shorten hospital stays, prehabilitation improved the six-minute walk distance preoperatively and maintained benefits at four weeks post-surgery. High…
A randomized controlled trial with 231 medical students found that while 3D immersive videos led to lower immediate knowledge retention compared to 2D videos, they significantly improved expected preparedness, satisfaction, and self-confidence after one month. Participants using 3D video reported feeling more engaged, better able…
A Phase II trial demonstrated that combining irreversible electroporation (IRE) with β-glucan significantly improved disease-free intervals and overall survival in patients with stage III pancreatic ductal adenocarcinoma. The study included 30 patients treated with IRE followed by β-glucan, showing a median disease-free interval of 18…
A novel nomogram has been developed to predict postoperative pneumonia risk after esophageal endoscopic submucosal dissection (ESD). In a cohort of 492 patients, the incidence of pneumonia was 18.6%. Key predictive factors included female sex, older age, low serum albumin levels, prolonged operative duration, muscular…
Analysis of 6,400 esophageal adenocarcinoma patients revealed that 51% experienced tumor downstaging after neoadjuvant chemoradiation, with complete downstaging noted in 5%. Downstaging correlated with a 31% and 17% reduced risk of death compared to disease progression and stable staging, respectively. Additionally, robotic-assisted minimally invasive esophagectomy…
Observational data indicate that pancreatic resections for neuroendocrine tumors (pnet) result in a significantly lower rate of ideal outcomes compared to pancreatic ductal adenocarcinoma (pdac) patients. The ideal outcome rate was 47.7% for pnet versus 55.7% for pdac, primarily due to a fourfold increase in…
A study involving 275 colorectal cancer patients revealed that early postoperative refeeding significantly reduces the risk of infectious complications and hospital stays exceeding five days. Specifically, late refeeding, use of nasogastric tubes, and intra-abdominal drains were identified as factors that increase complications. The findings indicate…
A novel EUS-guided technique utilizing lumen-apposing metal stents effectively treated patients with concomitant gastric outlet and biliary obstructions. In a study involving nine severely ill individuals, complete resolution of jaundice was achieved in all cases, attributed to successful transduodenal ERCP via gastroduodenal stenting. Post-procedure evaluations…
A risk stratification model for surgical adverse events (SAEs) in minimally invasive esophagectomy (MIE) was developed and validated using data from 747 patients. The model identified key risk factors, including chronic obstructive pulmonary disease and low albumin levels, achieving areas under the curve of 0.889…
