Researchers identified a pancreatic juice-specific fluorescent probe, selectively targeting ectonucleotide pyrophosphatase/phosphodiesterase (enpp) 1, from a library of 411 enzyme-activatable fluorescent probes. The probe demonstrated high reactivity with pancreatic juice, providing the potential for visualizing pancreatic juice leakage during surgery. This advancement may assist surgeons in addressing leaking sites and evaluating the need for prophylactic abdominal […]
Category: General Surgery
Hybrid ESD proves efficient for specific colorectal tumors
A multicenter study involving 890 patients evaluated hybrid endoscopic submucosal dissection (ESD) against conventional ESD for treating laterally spreading tumors (LSTs). Hybrid ESD demonstrated significantly reduced procedure times and hospitalization costs, particularly for lesions sized 10-30 mm. However, it yielded lower R0 resection rates and lifting sign positivity. For larger lesions, conventional ESD maintained better […]
New treatment guidelines enhance management of esophageal and gastric cancer.
Comprehensive updates on the treatment of esophageal and gastric cancer emphasize the crucial role of perioperative systemic therapy. Neoadjuvant chemoradiotherapy followed by postoperative immunotherapy is standard for locally advanced squamous cell carcinoma, while perioperative FLOT chemotherapy shows superior outcomes for adenocarcinoma. Promising results are also noted for MSI-high tumor patients receiving neoadjuvant immunotherapy. The focus […]
Minimally invasive approach linked to higher complications in pancreatic surgery
A cohort analysis of 1,130 patients with postoperative pancreatic fistulas (popf) found that those undergoing minimally invasive pancreatoduodenectomy (mipd) faced a significantly higher risk of additional complications compared to traditional open procedures (opd). Notably, 55% of mipd-popf patients encountered a secondary complication, including a higher occurrence of postpancreatic hemorrhage (21% vs 8%). Mipd also resulted […]
Telementoring enhances surgical skills in rural hospitals
A surgical telementoring system significantly improved surgical skills and job interest among medical students in rural Japan. Surgeons reported enhanced mental performance and reduced frustration when using the telementoring system. Furthermore, a substantial increase in interest for rural hospital work was noted among medical students after the experience, with more expressing a desire to pursue […]
XR technologies enhance surgical training effectiveness and acceptance
An umbrella review of 44 studies highlights the significant potential of extended reality (XR) technologies in surgical training, particularly for orthopedics, neurology, and laparoscopy. Findings revealed that XR improves surgical skills and procedural accuracy while reducing risks and operating room time. User-friendly systems increased accessibility for trainees across skill levels, and positive reinforcement from experienced […]
Oral antibiotics may replace surgery for uncomplicated appendicitis.
A clinical trial is set to evaluate the efficacy of oral moxifloxacin versus placebo in treating uncomplicated acute appendicitis without hospitalization. Targeting adults aged 18-60, the APPAC IV trial will assess treatment success 30 days post-discharge, aiming to determine if antibiotics and inpatient care can be safely eliminated. This noninferiority trial, conducted across nine Finnish […]
Primary anastomosis shows better outcomes in sigmoid volvulus surgery
In a comprehensive analysis of 1,083 sigmoid volvulus cases treated over 58 years, primary anastomosis emerged as the superior technique compared to stoma creation following urgent sigmoidectomy. Key findings include significantly lower complication rates, shorter hospitalization durations, and reduced costs associated with primary anastomosis. Notably, patients undergoing primary anastomosis experienced fewer incidents of shock, bowel […]
Consensus Established on Neoadjuvant Therapy for Pancreatic Cancer
Expert consensus has identified 82 best practices for delivering neoadjuvant therapy (NT) in localized pancreatic ductal adenocarcinoma (PDAC). Key areas include pre-NT evaluations, effective initiation and management during NT, and post-NT surgical and follow-up strategies. With 47 North American specialists involved, the findings aim to standardize care delivery, reduce variation, and potentially improve patient outcomes. […]
Need for Standardized Robotic Training Curriculum Identified
A survey involving 1,045 gastrointestinal surgery professionals across 38 European countries revealed a significant knowledge gap regarding dedicated robotic training programs. Notably, 68% of experts and trainees were unaware of such curricula, and 48% of trainees with robotic access had not performed any robotic surgeries. Participants emphasized the necessity for early engagement in bedside assisting […]