Newsletter
Best Papers in General Surgery
The five that matter, every day.
A study analyzing 1,001 pancreas ductal adenocarcinoma patients found that those from less marginalized backgrounds, indicated by the Area Deprivation Index (ADI), were 1.57 times more likely to attend follow-up appointments post-surgery compared to marginalized individuals. The study highlights significant disparities in patient follow-up rates,…
A study revealed that the immature granulocyte percentage serves as a reliable biomarker for distinguishing complicated from uncomplicated acute appendicitis. With a specificity of 92% at a cut-off value of 0.6, this biomarker outperformed other indicators, such as the immature granulocyte count and procalcitonin levels.…
Colorectal cancer patients with mature tertiary lymphoid structures (TLS) demonstrated notably improved outcomes, including reduced rates of vascular tumor thrombus, lymph node, and liver metastasis. An analysis of 230 specimens revealed that mature TLS correlated with lower Ki-67 expression and higher levels of deficient mismatch…
A novel deep-learning model, Recurr-Net, significantly outperformed traditional methods in predicting hepatocellular carcinoma (HCC) recurrence post-curative surgery. Analyzed across 1,231 patients, Recurr-Net demonstrated an area under the receiver operating characteristic curve (AUROC) of 0.770 to 0.857 internally and 0.758 to 0.798 externally, while the historical…
A multisocietal consensus has endorsed cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for treating diffuse malignant peritoneal mesothelioma (DMPM). An expert panel, acknowledging the limited efficacy of systemic chemotherapy, strongly recommended this approach for a select subgroup of patients. Despite low evidence certainty, the…
A study examining pain management in ventral hernia repair found that female patients were less likely than male patients to receive an opioid-sparing regimen despite showing a higher analgesic response and lower morphine consumption postoperatively. Specifically, only 62.27% of females were offered opioid-sparing pain regimens…
A study analyzing 335 patients undergoing Da Vinci surgery revealed that 195 experienced pressure injuries, identifying key risk factors including age, surgery duration, BMI, and the presence of a nasogastric tube. Through logistic regression analysis, researchers established a reliable prediction model to assess pressure injury…
A randomized clinical trial involving 260 patients revealed that primary needle-knife fistulotomy (PNKF) significantly outperforms standard transpapillary (STP) techniques for cannulating long-size papilla. PNKF achieved a biliary cannulation success rate of 96.2% compared to STP's 87.7% (p = 0.01). Moreover, post-endoscopic retrograde cholangiopancreatography pancreatitis was…
Laparoscopic liver resection (LLR) demonstrated superior clinical and economic outcomes compared to open liver resection (OLR) in a study involving 920 patients. LLR resulted in significantly fewer postoperative transfusions, a shorter median length of stay, and lower rates of complications, readmissions, and reoperations. Importantly, LLR…
A new deep learning model demonstrated strong predictive capabilities for mismatch repair deficiency in colorectal cancer. An area under the receiver operating characteristic (AUROC) score of 0.948 was achieved during testing, while independent validation yielded an AUROC of 0.807. Notably, the model achieved a negative…
