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Best Papers in General Surgery
The five that matter, every day.
Analysis of nearly 1 million patients revealed specific factors predicting postoperative bleeding after minimally invasive bariatric surgeries. Key predictors identified include preoperative anticoagulation, renal insufficiency, history of deep vein thrombosis (DVT) and pulmonary embolism (PE), presence of a cardiac stent, and a BMI of 40…
A collaborative initiative significantly enhanced trauma care in Ukraine through the implementation of advanced trauma life support (ATLS) courses amid ongoing conflict. Over three months, 213 healthcare providers participated in ten courses, showing measurable improvements in knowledge and self-reported confidence in trauma management. The program…
Endoscopic retrograde appendicitis therapy (ERAT) emerges as a promising alternative for managing acute or chronic appendicitis, allowing effective elimination of obstructions through endoscopic techniques. Compared to antibiotic therapy, patients undergoing ERAT showed lower rates of recurrence and avoided the need for appendectomy. Innovations like the…
A novel predictive tool combining early warning scores and C-reactive protein levels has been developed to detect anastomotic leakage after colon cancer surgery. Analysis of 1,855 patient records revealed that mean CRP levels exceeded 200 mg/l and early warning scores above 2 indicated leakage. Specifically,…
A machine learning model utilizing CT-based radiomics significantly surpassed traditional radiologist assessments in estimating pathologic response of colorectal liver metastases after neoadjuvant therapy. In a study involving 85 patients, the model achieved an area under the curve (AUC) of 0.87, contrasting sharply with the AUCs…
A meta-analysis of 12 randomized controlled trials involving 1,181 gastric cancer patients demonstrated that hyperthermic intraperitoneal chemotherapy (HIPEC) significantly improved survival rates compared to control groups at 1, 2, 3, and 5 years. The recurrence rates were notably lower in the HIPEC group, and higher…
A comprehensive meta-analysis identified several modifiable environmental factors associated with gallbladder cancer (GBC). Key risk factors included body mass index, waist circumference, and bile duct infections, all showing moderately high credibility in longitudinal studies. Interestingly, higher education levels correlated with reduced GBC risk. With 350…
A significant proportion of rectal cancer patients exhibit isolated lateral lymph node (LLN) metastases without mesenteric involvement. Results indicate these patients have a markedly better prognosis, with three-year overall survival rates of 85% compared to 51% for those with both LLN and mesenteric metastases. Furthermore,…
A logistic regression model developed from various risk factors effectively predicts early esophageal cancer with submucosal infiltration beyond 200 micrometers. Key predictive factors include endoscopic findings, esophageal wall thickening, pickled food intake, platelet-lymphocyte ratio, tumor size, circumferential mucosal defect percentage, and preoperative pathological type. The…
In a comparison of minimally invasive common bile duct exploration (MICBDE) and endoscopic retrograde cholangiopancreatography (ERCP) for treating choledocholithiasis, significant advantages were found for MICBDE. Fluoroscopy time was notably lower for MICBDE (1.54 minutes) compared to ERCP (3.1 minutes, p
