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Best Papers in General Surgery
The five that matter, every day.
A study involving 302 patients with advanced resectable esophageal cancer revealed that preoperative dysphagia scores are crucial prognostic factors for survival outcomes. Patients with higher dysphagia scores (2-4) exhibited significantly poorer disease-free and overall survival rates compared to those with scores of 0-1. Specifically, 5-year…
A single-center experience with hepatic artery infusion pump therapy for unresectable colorectal liver metastases showed successful placement in most patients, with a complication rate of 37.5%. The median overall survival (OS) from diagnosis was 55.2 months, though concurrent primary tumor resection led to inferior OS…
Analysis of 196 patients with oesophagogastric adenocarcinoma revealed a 13.8% early recurrence rate post-surgery, with a one-year recurrence-free survival of 83.7% and overall survival of 90.8%. The study identified extracapsular spread and ypN3 stage as independent risk factors for early recurrence, highlighting their significance in…
A systematic review and meta-analysis compared endoscopic nasobiliary drainage (ENBD) and percutaneous transhepatic cholangial drainage (PTCD) in advanced hilar cholangiocarcinoma patients. Results indicated PTCD had a significantly higher success rate and was more effective in lowering total bilirubin levels post-drainage. While ENBD showed a lower…
A shift towards neoadjuvant therapy in resectable pancreatic adenocarcinoma may enhance surgical success rates. This approach addresses micro-metastatic disease present in many patients, highlighting the necessity of systemic therapy irrespective of resectability. It further allows for tailored treatment selections based on individual tumor biology. Evidence…
A novel robotic purse-string suture technique applied during intracorporeal anastomosis showed promising results for rectal and sigmoid colon cancer surgeries. In a matched cohort analysis of 46 patients, those who underwent the purse-string method exhibited significantly reduced blood loss and shorter operative times compared to…
Analysis of 364 hepatocellular carcinoma patients revealed that age alone does not significantly affect overall or tumor-free survival outcomes after liver resection. Higher postoperative morbidity and longer hospital stays were observed in younger patients under 60, while the elderly exhibited no early mortality. Despite higher…
A nationwide analysis revealed that 53.3% of elderly patients hospitalized with acute colonic diverticulitis were frail. In a matched cohort study, frail patients faced higher mortality rates, extended hospital stays, and increased median inpatient costs. They also experienced more complications, including sepsis, acute kidney injuries,…
A retrospective analysis of 21 cases demonstrated the successful application of microvascular surgical principles in addressing arterial and venous insufficiencies during major gastrointestinal resections. Out of these, 20 organs were salvaged, showcasing the effectiveness of methods such as vessel repair and interposition grafts. The results…
Outpatient antibiotic intake post-surgery negatively impacts the three-year disease-free survival (DFS) in colorectal cancer patients. Among 35,496 individuals, 79% received antibiotics, with specific classes such as cephalosporins and quinolones linked to increased risk of recurrence. The effects varied based on tumor location and disease stage,…
