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Best Papers in General Surgery
The five that matter, every day.
A systematic review and meta-analysis involving 930 patients revealed that anatomic resection (AR) significantly enhances both overall survival (OS) and disease-free survival (DFS) compared to non-anatomic resection (non-AR) for resectable intrahepatic cholangiocarcinoma. The OS rates at 1, 3, and 5 years were 71.5%, 46.1%, and…
A recent analysis of 1,178,090 patients reveals that those undergoing sleeve gastrectomy or Roux-en-Y gastric bypass with preoperative therapeutic anticoagulation face significantly higher risks of postoperative complications. Specifically, these patients exhibited increased rates of anastomotic leaks, deep vein thrombosis, and gastrointestinal bleeding, as well as…
The study finds no significant correlation between body mass index (BMI) and perioperative outcomes or short-term recurrence after paraesophageal hernia repair in a cohort of 884 patients. Key metrics such as blood loss, length of hospital stay, major complications, and mortality were unaffected by increasing…
A study analyzing 232 patients undergoing endoscopic full-thickness resection (EFTR) demonstrates its feasibility, safety, and effectiveness for treating upper gastrointestinal submucosal tumors, including predominantly extraluminal lesions. The procedure achieved an en-bloc resection rate of 98.7%, with a negligible recurrence observed over a mean follow-up of…
A study involving 1511 major hepatectomies found that preoperative future liver remnant (FLR) volume assessment significantly impacts posthepatectomy liver failure (PHLF) risk. High-risk patients with FLR
Incorporating a systemic oxidative stress score (soss) based on fibrinogen, albumin, and cholesterol significantly enhances prognostic accuracy for gastric cancer patients post-radical gastrectomy. Among 3,820 patients, nomograms utilizing soss outperformed traditional staging methods in predicting overall and disease-free survival (AUC: 0.830 vs. 0.778, AUC: 0.824…
A multicenter study evaluated the ADV score's efficacy in identifying hepatocellular carcinoma (HCC) patients at high risk of recurrence. The analysis involved 755 patients and established risk groups based on microvascular invasion and Edmonson-Steiner grade. Results showed that the ADV score differentiates these groups effectively,…
A novel nomogram utilizing the number of positive lymph nodes has demonstrated effectiveness in predicting overall survival (OS) for patients with pancreatic head cancer following radical surgery. Analyzed data from over 3,200 patients identified key independent risk factors, including age, tumor extent, and chemotherapy. The…
Enhanced recovery after surgery (ERAS) significantly improves clinical outcomes, patient satisfaction, and reduces medical costs. While traditionally implemented in numerous surgical specialties, recent advancements have led to ERAS protocols being adapted for new surgeries, including pediatric and robotic-assisted procedures. Although the overall costs are higher…
An analysis of 48,032 trauma patients revealed that 22% experienced complications, leading to a 1.32-fold increase in hospitalization costs. The study identified specific groups at higher risk, such as elderly women with pelvic trauma being more prone to thrombosis and younger men facing respiratory insufficiency…
