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Best Papers in General Surgery
The five that matter, every day.
A combined nomogram integrating IVIM-DWI parameters and MRI characteristics achieved AUC values of 0.901 and 0.883 in training and validation cohorts, respectively. This approach effectively distinguishes between T1-2 and T3-4 stages of gastric cancer, addressing the challenge faced by radiologists in preoperative assessments. No significant…
Camrelizumab plus apatinib in a real-world setting has shown significant benefits in recurrence-free survival (RFS) for patients with hepatocellular carcinoma (HCC) with microvascular invasion following radical resection. The comparison between adjuvant therapy (99 patients) and observation (172 patients) indicated a hazard ratio of 0.52 for…
Validation of 3D virtual modelling (3DVM) demonstrated a 96% accuracy for identifying arteriovenous variations in laparoscopic complete mesocolic excision with central vascular ligation (CMECVL) among 26 patients. Compared to 49 standard mesocolic excision controls, CMECVL showed no intraoperative complications and similar 30-day morbidity rates, although…
Findings from a retrospective analysis of 81 patients reveal a 25.9% recurrence rate and a 16.0% complication rate for large parastomal hernia repairs using lap-re-do techniques. Notably, the lap-re-do Sugarbaker technique demonstrated a significantly lower recurrence rate of 12.2% compared to 40% for the Keyhole…
This meta-analysis compared robotic-assisted natural orifice specimen extraction (NOSE) with traditional robotic transabdominal wall specimen retrieval (TWSR) in colorectal cancer surgeries involving 717 patients. Findings revealed that the NOSE technique resulted in significantly lower overall postoperative complications (OR 0.55; p=0.01) and indicated its safety and…
A computer vision algorithm was developed to predict superior mesenteric artery (SMA) margin status in pancreatic ductal adenocarcinoma patients using preoperative CT scans. In a study involving 200 patients, the algorithm achieved a sensitivity of 0.43, outperforming radiologists (0.23) and surgeons (0.36). Specificity was high…
Preoperative hypoalbuminemia is linked to higher 30-day mortality and complications after esophagectomy. In a study involving 803 patients with hypoalbuminemia compared to 7046 controls, matched analyses revealed mortality rates of 4.48% for those with low albumin versus 3.00% for those without. Findings suggest that recognizing…
The study established tumor fibrosis as an independent prognostic factor for survival in pancreatic ductal adenocarcinoma (PDAC) patients, identifying a 40% collagen fraction cut-off value crucial for prognosis differentiation. Utilizing a CT-based radiomics model, researchers achieved areas under the curve of 0.825 and 0.745 in…
Achieving complete pathologic response in esophageal adenocarcinoma is linked to a notable survival benefit. Among 16,169 patients analyzed, 11.4% achieved this response, rising to 17.5% in those diagnosed from 2016 to 2020. Key independent predictors included female sex, black race, Hispanic ethnicity, and clinical stage…
A systematic review of 37 studies highlights that colorectal cancer incurs substantial direct and indirect costs, primarily driven by direct medical expenses such as hospitalization, surgery, and chemotherapy. Face significant financial impacts are experienced by families, the health system, and broader society. The findings advocate…
