A new lasso-logistic regression model was developed and validated, identifying nine independent risk factors for postpancreatectomy hemorrhage among 9,631 patients across two cohorts. The model demonstrated strong predictive accuracy, achieving an area under the receiver operating characteristic curve of 0.87 during external validation, significantly outperforming previous prediction models (p
Category: General Surgery
Early surgery after 3 months of neoadjuvant therapy best for pancreatic cancer.
In a study of 282 patients with borderline resectable pancreatic cancer, those undergoing neoadjuvant treatment (NAT) followed by surgery exhibited the best overall survival (OS) of 35 months compared to 23 months for upfront surgery and 16 months for chemotherapy only. Patients receiving at least 3 months of NAT showed significantly improved OS, while those […]
Adjuvant chemo improves survival in high-risk rectal cancer patients.
In patients with stage IIA rectal cancer above the peritoneal reflection who did not receive preoperative chemoradiotherapy, adjuvant chemotherapy (AC) demonstrated significantly improved 5-year overall survival (93.2% vs. 84.6%, p = .001) and recurrence-free survival (81.6% vs. 64.1%, p = .01). Patients with one or more risk factors showed marked benefits from AC compared to […]
Lymph node metastasis differs significantly between gastric carcinoma types.
A study of 891 Chinese patients revealed distinct risk factors for lymph node metastasis (LNM) and prognosis in submucosal early gastric cardiac (SEGCC) versus noncardiac (SEGNCC) carcinomas. Elderly patients and specific tumor characteristics were more prevalent in SEGCC, which correlated with poorer prognoses. Univariate and multivariate analyses identified female sex and lymphovascular invasion as key […]
Task-specific metrics effectively evaluate perineal proctectomy skills
The study established and validated task-specific metrics for assessing performance in perineal proctectomy, a complex surgical procedure. In three phases, 23 expert colorectal surgeons reached consensus on the metrics, and a subsequent assessment of 22 participants indicated a strong correlation between global and task-specific scores (rs = 0.86; p
Intracorporeal anastomosis shows improved outcomes in colon surgery
A cohort study found that minimally invasive left colectomy using total intracorporeal anastomosis (TIA) resulted in fewer intraoperative complications and comparable postoperative morbidity compared to extracorporeal anastomosis (EA). Among 246 patients, TIA demonstrated higher C-reactive protein levels and reduced relevant anastomotic bleeding but similar anastomotic dehiscence rates. These results suggest TIA’s technical feasibility and safety, […]
Adjuvant therapy enhances survival in high-risk periampullary cancer.
Evidence from a multi-institutional cohort study indicates that adjuvant therapy significantly improves overall survival rates in patients with high-risk periampullary adenocarcinomas. Among 736 patients analyzed, those receiving adjuvant therapy had a median overall survival of 68.7 months compared to 61.1 months for those under observation, translating to a hazard ratio of 0.73. Additionally, nodal involvement […]
Global burden of appendicitis shows steady decline but regional disparities persist
Between 1990 and 2021, the global burden of appendicitis displayed a significant decline in mortality and disability-adjusted life-years (DALYs), yet regional disparities in incidence and mortality persist. In 2021, global age-standardized mortality was 0.358 per 100,000, with the highest incidence rates in high-income Asia Pacific. While overall trends indicate improvement, nearly half of the regions […]
Greater team member familiarity enhances effectiveness in operating rooms
Findings indicate that team member familiarity directly enhances perceived team effectiveness in operating rooms. This relationship is significantly mediated by shared mental models and mutual trust among team members. Data from two hospitals reveal that individual variance primarily drives perceived effectiveness, with a smaller portion (12%) attributed to operating room level factors. To improve overall […]
Minimally invasive distal pancreatectomy is linked to lower mortality.
A comparison of distal pancreatectomies across North America and Europe revealed that minimally invasive techniques were performed in 36% of cases, varying from 29% to 54% among regions. This approach demonstrated significantly lower 30-day mortality (odds ratio 1.633) and fewer severe complications in North America and Germany compared to open surgery. Notable patient demographic differences […]