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Best Papers in General Surgery
The five that matter, every day.
Assessment of drain fluid amylase levels on days one and three provides a reliable estimate of the risk for clinically relevant postoperative pancreatic fistula (CR-POPF) after pancreatoduodenectomy. A study of 923 patients showed that integrating both dfa1 and dfa3 into a predictive model yielded a…
Achieving textbook outcomes significantly enhances long-term survival among gastric cancer patients, with a notable 5-year conditional overall survival of 64.7% compared to 40.2% for those who did not meet these criteria (p < .001). Additionally, there is a compelling difference in 5-year conditional disease-free survival,…
A systematic review and meta-analysis of 13 studies revealed polymeric clips significantly reduced surgical time compared to endoloops during laparoscopic appendectomy for uncomplicated appendicitis (standardized mean difference 0.37, p < .00001). No notable differences were observed in hospital stay or overall complications. However, the endoloop…
The ISGACA initiative successfully united over 60 medical centers globally, gathering data from 4,309 patients to enhance treatment strategies for non-pancreatic periampullary cancers. By establishing a structured methodology, the group facilitated nine publications, secured research grants, and initiated a prospective multicenter clinical trial. The collaborative…
Utilization of near-infrared fluorescence imaging during laparoscopic hepatectomy significantly improved tumor identification and secured clear resection margins in colorectal liver metastasis. Of the 94 tumors, fluorescence imaging detected 56 (59.6%), resulting in a 96.6% clear margin success rate for the 59 patients studied. Pathological assessment…
Direct visualization endoscopic retrograde appendicitis therapy effectively diagnosed acute uncomplicated appendicitis in 35 of 36 patients (97.2%). The mean procedure time was 13.1 minutes, with a low complication rate. One patient required a laparoscopic appendectomy after experiencing recurrent abdominal pain. The average length of hospital…
A simple predictive model for early recurrence of hepatocellular carcinoma (HCC) post-liver resection has been developed. Based on an analysis of 1,133 patients, five key prognostic factors—alpha-fetoprotein levels and AJCC stage—were identified. Among the cohort, 35.1% experienced early recurrence within two years, with respective two-year…
Findings from 19 systematic reviews indicate that using surgical mesh significantly lowers the risk of both clinically and radiologically detected parastomal hernias. The pooled hazards ratio for clinically detected hernias was 0.33, while it was 0.55 for radiologically detected hernias. Additionally, mesh use was associated…
In a systematic review of 738 pancreatic head cancer patients, total mesopancreas excision (TMPE) significantly increased R0 resection rates (RR 1.24) and reduced overall (RR 0.53) and local recurrence rates (RR 0.39) compared to standard pancreatoduodenectomy. TMPE also reduced blood loss (MD -143.70 ml) and…
A combined nomogram integrating IVIM-DWI parameters and MRI characteristics achieved AUC values of 0.901 and 0.883 in training and validation cohorts, respectively. This approach effectively distinguishes between T1-2 and T3-4 stages of gastric cancer, addressing the challenge faced by radiologists in preoperative assessments. No significant…
