Newsletter
Best Papers in General Surgery
The five that matter, every day.
A multicenter cohort study analyzed 1,954 adults with severe blunt trauma, revealing that a high fresh frozen plasma (FFP) to red blood cell (RBC) ratio (greater than 1) was associated with lower in-hospital mortality (OR 0.73). This suggests that patients receiving a higher FFP ratio…
A survey involving 1,024 surgeons revealed that 63% are motivated to improve surgical sustainability; however, less than 10% can estimate the carbon footprint of their practices. Most respondents are unconcerned about negative impacts from sustainability efforts, indicating a readiness to implement proposed changes. Preferred educational…
The study demonstrated that circulating tumor DNA (ctDNA) methylation analysis is a valuable prognostic tool for long-term outcomes in stage IV colorectal cancer. Patients with high levels of CHFR-rmv experienced significantly worse recurrence-free survival compared to those with low levels (p = 0.001), establishing CHFR-rmv…
Findings indicate that non-Hispanic Black patients with colon cancer treated at Commission on Cancer (CoC)-accredited hospitals received significantly more guideline-concordant care than those treated at non-accredited facilities. Specifically, the odds of undergoing necessary lymphadenectomy and chemotherapy were higher (adjusted odds ratios of 1.89 and 2.31,…
A mortality prediction model was developed for patients with intra-abdominal hypertension (IAH) utilizing abdominal perfusion pressure (APP) and advanced AI techniques. The study analyzed 1,354 patients, revealing that APP < 60 mmHg was linked to higher mortality rates within 7 to 90 days. The machine…
Changes in skeletal muscle quality (δmimac) post-gastrectomy were associated with prognosis in early gastric cancer (EGC) patients, contrary to body weight (δbw) changes. Statistical analyses demonstrated that δmimac was significantly correlated with survival outcomes (p = 0.037), while δbw was not (p = 0.243). The…
Findings revealed that among Medicare patients undergoing colectomy for colon cancer, those in the highest social vulnerability quintile faced a greater likelihood of unplanned surgeries (35.6% vs. 28.9%) and higher 30-day (3.4% vs. 2.9%) and 1-year mortality rates (10.8% vs. 8.6%). The adjusted odds ratios…
A study of 3,020 stage III rectal cancer patients identified that 12.4% had a positive circumferential resection margin (CRM). Notably, CRM involvement predominantly occurred through primary tumor invasion (63.2%). Local recurrence and distant metastasis rates varied, being lowest with lymph node metastasis and highest with…
Among 143,582 patients undergoing digestive cancer surgery, those treated at high-volume centers experienced significantly lower 90-day mortality rates compared to low-volume centers. Univariate analysis revealed mortality rates of 5.06% at high-volume centers vs. 7.23% at low-volume centers for gastric surgeries and similar trends across other…
An observational cohort study evaluated a standardized perioperative protocol for pancreatic oncological surgery from 2015 to 2022, finding significant reductions in postoperative complications. The rate of grade B and C pancreatic fistulas was 4.2%, while postoperative hemorrhage and delayed gastric emptying occurred in 2.5% and…
