Newsletter
Best Papers in General Surgery
The five that matter, every day.
In a comprehensive study of 367,887 patients, findings reveal that women are 44% more likely than men to receive cancer surgery. However, the likelihood decreases for both sexes with age and increasing co-morbid conditions, particularly among women. Men display higher rates of 90-day reoperations (21.2%)…
Social-environmental inequalities significantly impact surgical outcomes, as revealed by the analysis of 1,052,040 Medicare beneficiaries. Patients from areas marked by greater environmental injustice showed reduced chances of achieving textbook surgical outcomes (odds ratio 0.95) and lower likelihood of safe discharge (odds ratio 0.97). Both outcomes…
A nomogram was developed to predict postoperative complications in 207 patients with middle and low rectal cancer undergoing transanal total mesorectal excision (TATME). Findings indicated that 27.5% of patients experienced complications. Key predictors included operation time, smoking history, anastomotic technique, and ASA score, each significantly…
A systematic review and meta-analysis of six randomized trials, including 1949 patients, demonstrated that indocyanine green (ICG) fluorescence significantly reduces anastomotic leak rates in left-sided colorectal resections. The pooled odds ratio showed a 4.7% absolute reduction in leak rates (OR: 0.586, 95% CI: 0.434-0.792), indicating…
A study involving 200 patients undergoing laparoscopic pancreatoduodenectomy demonstrated that 82.5% achieved a textbook outcome, indicating a smooth recovery without specified complications. Key independent risk factors included a higher likelihood for female patients and those with hard pancreatic texture. These findings suggest that specific patient…
Higher county-level provider density significantly correlates with lower hepatobiliary cancer incidence and mortality. Analysis across 1,359 counties revealed that areas with low provider density suffered higher rates of all-stage and late-stage cancer incidence, along with increased mortality rates. Notably, moderate and high provider density were…
Oral carbohydrate loading before elective colorectal surgery significantly reduces postoperative insulin resistance, inflammatory markers, and improves patient well-being. In a randomized controlled trial with 72 participants, the carbohydrate loading group showed a marked decrease in insulin resistance on the day of surgery and postoperatively. Additionally,…
Among 339 patients with locally advanced rectal cancer, 208 (61.3%) completed total neoadjuvant therapy, achieving a final complete response (CR) rate of 42.3%. Notably, 57 patients (27.4%) sustained clinical CR for over a year, while 42 patients showed pathologic CR post-surgery. Predictors of CR included…
A multicenter study revealed that conversion surgery following FOLFIRINOX or gemcitabine plus nab-paclitaxel chemotherapy significantly improves overall survival in patients with initially unresectable pancreatic cancer. The surgery group demonstrated a median overall survival of 34.4 months, compared to 19.8 months in the control group (hazard…
CT-guided core needle biopsy (CNB) demonstrates high diagnostic yield and safety in pancreatic tumor evaluation. In a study of 43 biopsies across 42 patients, histological diagnosis was achieved in 93% of cases. CNB exhibited a sensitivity of 93%, specificity of 100%, and overall accuracy of…
