Newsletter
Best Papers in General Surgery
The five that matter, every day.
A novel protocol for germline genetic testing (GGT) in pancreatic ductal adenocarcinoma (PDAC) demonstrated a high patient compliance rate of 98.7%, with 310 patients tested over three years. The physician compliance rate was 82.6%, and 14.2% of patients had actionable pathogenic variants. The protocol effectively…
Modified Surgical Apgar Score (MSAS) may serve as a valuable tool in predicting postoperative complications in rectal cancer patients undergoing robotic surgery. The study analyzed 524 patients, revealing a 17.4% complication rate, with MSAS scores of 6 identified as optimal cut-off values. The area under…
Patients undergoing pyloroplasty for gastroparesis showed significant symptom improvement, with a GCSI score reduction from 3.5 to 2.7 at 18.7 months. However, 28.8% required gastric stimulation due to inadequate recovery. Patients who needed adjunct stimulation were younger and had higher baseline GCSI scores. Following gastric…
The study validates the European Hernia Society classification for parastomal hernias (PH) by analyzing 160 cases at a single center. It demonstrates that this classification effectively categorizes PH, essential for surgical planning and anticipating complications. Findings reveal a high incidence of complex type III and…
Co-transplantation of adipose tissue-derived mesenchymal stem cells (ADMSCs) with pancreatic islets into decellularized pancreatic skeletons improved vascularization and preserved islet morphology. While ADMSCs did not suppress immune responses in vivo, their presence reduced the proliferation of splenocytes in vitro. In contrast, endothelial cell co-transplantation resulted…
Participants receiving probiotic supplementation alongside a weight loss program and cognitive behavioral therapy experienced significantly greater reductions in weight, body mass index, and fat mass compared to the placebo group (pā
A nomogram combining circulating tumor cells (CTC) from the first drainage vein and clinical parameters was developed to predict liver metastasis in colorectal cancer (CRC) patients. Analysis of data from 343 patients revealed that higher CTC levels correlated with liver metastasis. Key identified predictors included…
A multicenter study analyzed 535 patients with single large hepatocellular carcinoma (slhcc). Results indicated that major hepatectomy led to significantly higher major complications and no long-term survival benefits compared to minor resections, especially left lateral sectionectomy, which was associated with better overall survival (p=0.02). The…
A systematic review of 26 studies revealed that surgical smoke (ss) harbors various infectious viruses, including human papillomavirus (HPV), HIV, varicella zoster, hepatitis B, SARS-CoV-2, and oral poliovirus. These findings indicate a potential transmission risk to healthcare workers in operating rooms during procedures involving smoke-producing…
Patients aged 65 and older with acute appendicitis presented later, requiring more diagnostic imaging and experiencing higher rates of complications compared to younger adults. The study revealed that elderly individuals had longer symptom durations (7.88 days vs. 3.56 days) and required CT scans more frequently…
