Newsletter
Best Papers in General Surgery
The five that matter, every day.
A modified dosing protocol (MDP) for hepatic arterial infusion (HAI) with reduced floxuridine starting dose resulted in fewer dose holds and reductions compared to the standard dosing protocol (SDP). MDP patients completed more cycles before dose reduction, received more overall cycles, and had fewer instances…
In a study of 1,958 colon cancer patients, a lower distal resection margin distance, advanced N stage, and fewer lymph nodes dissected were associated with increased risk of anastomotic recurrence (AR). The 3-year AR risk was lowest when the proximal resection margin was ≥6 cm,…
Bifurcated allogeneic vein grafts significantly reduce sinistral portal hypertension (SPH) in pancreatic carcinoma patients post-pancreaticoduodenectomy with spleno-mesenterico-portal (SMP) confluence resection. Retrospective analysis showed a lower SPH incidence in the reconstruction group (8.1% vs. 36.4%). Prospective data supported this, with only 6.7% SPH in patients undergoing…
Triple therapy with folfox-based hepatic arterial infusion chemotherapy, tyrosine kinase inhibitors, and PD-1 inhibitors significantly prolonged overall survival (24.6 vs 11.9 months) and progression-free survival (10.0 vs 7.7 months) compared to dual therapy. The triple-therapy group also had higher response rates and more patients converted…
Low preoperative platelet count and high serum CEA levels are significant predictors of poor disease-free and overall survival in early colorectal cancer patients (pT2N0M0 or pT3N0M0). Platelet count is a protective factor for disease-free survival, while CEA level is an independent risk factor for overall…
Patients undergoing late oral feeding post-esophagectomy had significantly less body weight loss, higher calorie and protein intake, and lower malnutrition rates compared to those with early feeding. Complication rates and hospital stays were similar between the groups, indicating that late oral feeding may improve postoperative…
OR Black Box technology assessed surgical safety checklist performance during a study comparing in-situ simulation intervention. The simulation group showed improved debrief quality (84% vs. 79%, p
Among 42 patients with type I gallbladder perforations, 28 underwent laparoscopic cholecystectomy (LC) and 14 had conversion to open cholecystectomy (COC). Significant differences included the location of perforations, with LC more common for fundal perforations, while COC was often required for neck perforations. LC had…
In a comparison of laparoscopic (LPD) versus open (OPD) pancreaticoduodenectomy for ampullary cancer, LPD showed longer operative times but less blood loss and shorter hospital stays. No significant differences were found in morbidity, survival rates, or recurrence-free survival between LPD and OPD. Both approaches had…
Experts from various specialties created a standardized system for reporting complications in inguinal lymph node dissection. Using a modified Delphi consensus approach, 47 consultants achieved unanimous agreement on defining and categorizing intraoperative and postoperative complications. The new system classifies postoperative issues into five macrocategories and…
