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Best Papers in General Surgery
The five that matter, every day.
Evaluation of tumor necrosis as a prognostic indicator in colorectal cancer led to the development of criteria for three assessment methods: average percentage, hotspot, and linear methods. All methods demonstrated independent predictive ability for colorectal cancer-specific survival, with the average percentage method showing the highest…
Significant increases in access to total neoadjuvant therapy for rectal cancer were noted in California, rising from 36.6% in 2010 to 66.3% in 2020, with no disparity in growth between racial and ethnic groups. However, Latino patients were less likely to receive this treatment compared…
An AI-powered mobile game, LapBot, was validated for teaching safe laparoscopic cholecystectomy skills. Among 903 global participants, increased game difficulty led to lower scores (p
The clinical study revealed that single-vessel transection Roux-en-Y reconstruction following total gastrectomy significantly shortened operation time (162.5 min vs. 178.5 min) and reduced intraoperative bleeding (167.2 ml vs. 207.8 ml) compared to conventional Roux-en-Y reconstruction in patients with proximal gastric cancer. No notable differences were…
A systematic review of eleven studies indicates curative-intent surgery for hepato-pancreato-biliary (HPB) cancers can yield statistically significant cures. Hepatocellular carcinoma showed cure fractions of 63.4% to 75.8% with liver transplantation and 31.8% to 40.5% with hepatic resection. Intrahepatic cholangiocarcinoma demonstrated a cure fraction of 9.7%…
Researchers found that adherence to specific components of an enhanced recovery program, including no nasogastric tube, early mobilization, early regular diet, postoperative multimodal analgesia, and early discontinuation of maintenance intravenous fluids, significantly reduced length of stay, readmission rates, and complication rates in colorectal surgery patients.…
Clinicians found that simple adrenal cysts smaller than 10 cm can be safely monitored without surgery. In a study of 77 patients, cysts under 10 cm grew slowly (0.3 cm/year) and showed no signs of malignancy or complications. Conversely, cysts over 10 cm grew significantly…
Among 3,728 primary hyperparathyroidism patients, those undergoing parathyroidectomy had reduced risks of new-onset cognitive impairment (HR: 0.65), somnolence (HR: 0.45), and schizophrenia (HR: 0.08) compared to nonoperative management. No significant risk reduction was observed for anxiety, depression, or suicidal ideation. Additionally, surgical patients were less…
A >50% decrease in intraoperative parathyroid hormone (iPTH) levels into the normal reference range predicts complete excision of malignancy in patients with parathyroid carcinoma. 93% of patients achieving normal iPTH levels had operative success, compared to only 50% of those with a >50% iPTH decrease…
AI-based multimodal multi-tasks analysis of 1,011 PTC patients reveals molecular subtypes, impact of BRAF mutations on lymph node metastasis and prognosis. Deep learning model predicts metastasis with high accuracy (AUC 0.86-0.93) and generates heatmaps to aid clinicians in identifying high-risk areas. Offers valuable insights for…
