Adjuvant chemoradiotherapy post-multiagent neoadjuvant chemotherapy in pancreatic cancer patients enhances survival, especially for those with lvi+ or grade iii tumors. While initial unadjusted analysis showed shorter median survival with chemoradiotherapy, adjusted results indicated a 25% risk reduction in mortality. Notably, patients with grade iii or lvi+ tumors reaped the most benefit from this combined adjuvant […]
Category: General Surgery
Cost-effectiveness of Liver Resection Techniques
Laparoscopic liver resection proves most cost-effective with lower total costs and superior postoperative outcomes compared to open and robotic liver resection. Open liver resection incurs the lowest procedural costs, but highest hospitalization costs. Robotic liver resection has the highest total and procedural costs but reduces hospitalization costs with advantages in mortality and length of stay. […]
Transanal Total Mesorectal Excision Yields Low Recurrence and High Survival Rates
High-volume centers in the USA saw positive results with Transanal Total Mesorectal Excision (TaTME) for rectal cancer. The study of 391 patients revealed low rates of local recurrence, high completion rates of TME specimens, and promising 3-year overall survival. These findings support the oncologic safety and perioperative benefits of TaTME when conducted by skilled surgeons […]
Pylorus Preservation in SG + LoopDJB Reduces Hypoalbuminemia Compared to OAGB
One anastomosis gastric bypass (OAGB) and sleeve gastrectomy with loop duodenojejunal bypass (SG + LoopDJB) demonstrate similar weight loss, type 2 diabetes remission, and lipidemia improvements at 1 year post-operation. OAGB presents higher hypoalbuminemia but lower gastroesophageal reflux disease symptoms compared to SG + LoopDJB. Pylorus preservation in SG + LoopDJB may reduce hypoalbuminemia risk, […]
Left-Sided Colon Cancer Shows Better Survival Than Rectal Cancer Post-Hepatic Metastasectomy
Survival outcomes differed between left-sided colon and middle/low rectal cancer post-colorectal hepatic metastasectomy. Patients with left-sided colon cancer exhibited significantly better overall survival (OS) than those with middle/low rectal cancer, especially in the subgroup analysis of ras mutations. The study suggests that middle/low rectal cancer should not be grouped together with left-sided colon cancer in […]
Whipple Over the Splenic Artery (WOTSA) as an Alternative to Total Pancreatectomy for PDAC
Whipple over the splenic artery (WOTSA) can replace most total pancreatectomies for ductal adenocarcinoma, offering similar complication rates but improved postoperative glycemic status and potentially better disease-free survival. Results show no reoperations required in the WOTSA group due to pancreas or spleen issues, with comparable operative outcomes to total pancreatectomy. Findings suggest WOTSA as a […]
Colorectal Carcinoma In Situ Can Metastasize and Recur
Colorectal carcinoma in situ can metastasize to lymph nodes and recur, challenging previous assumptions. Among 1069 patients, 0.46% experienced regional lymph node metastasis or recurrence, with cases identified during or after primary surgery. Distant metastases were also observed, emphasizing the need for careful assessment at diagnosis. This study highlights the importance of recognizing potential metastasis […]
Diagnostic Accuracy of Ultrasonography and Non-Contrast Computed Tomography in Acute Appendicitis
Ultrasonography and non-contrast computed tomography show high accuracy in diagnosing acute appendicitis, reducing negative laparotomy rates without increased risks. Computed tomography is superior to ultrasonography. The study compared sensitivity, specificity, and accuracy of both methods, indicating CT as a valuable second-line tool. With proper utilization of these imaging techniques, clinicians can effectively diagnose appendicitis and […]
Comparing Laparoscopic-guided vs Ultrasound-guided TAP Block in Cholecystectomy
Ultrasound-guided TAP block is often preferred, but laparoscopic-assisted TAP (LTAP) shows shorter administration time. Post-operative pain management, analgesic requirements, and nausea were similar between LTAP and ultrasound-assisted TAP (UTAP) groups. However, UTAP group had reduced nausea and vomiting instances. LTAP block is a viable alternative in the absence of ultrasound guidance, offering quick and efficient […]
Higher Chemotherapy Dose and Muscle Mass Improve Pancreatic Cancer Survival
Study finds higher relative dose intensity (RDI) of adjuvant S-1 chemotherapy and greater psoas muscle mass volume (PMV) linked to significantly improved 5-year overall and relapse-free survival rates in patients with resected pancreatic ductal adenocarcinoma. RDI emerges as an independent prognostic factor, with patients displaying high RDI and high PMV showing the best outcomes. Combining […]