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Best Papers in General Surgery
The five that matter, every day.
Deep learning models applied to prechemotherapy imaging accurately predict response to neoadjuvant chemotherapy in colorectal cancer liver metastases, outperforming clinical models. A study on 95 patients found the deep learning model had an AUC of 0.77, superior to the clinical model's AUC of 0.41, showing…
Identifying predictors of bile leakage after hepatectomy, researchers established criteria for safe early drain removal. Analyzing 351 patients, they found a drainage fluid direct bilirubin level cutoff of 0.16 mg/dl and volume cutoff of 125 ml on postoperative day 2. Patients meeting both criteria had…
Patients with colon cancer at high risk of recurrence benefit from preoperative evaluation, neoadjuvant chemotherapy, and revised intraoperative strategies. Specialized treatments, including hipec intraoperative chemotherapy, improve outcomes for patients with occult peritoneal metastases. Optimized cytoreductive surgical procedures and peritonectomy reduce sites of metastases, enhancing the…
Operating room black box technology allows for real-time monitoring of surgical procedures, improving transparency, and identifying areas for skill improvement. It enhances patient safety by providing a comprehensive analysis of clinical and non-clinical performances, offering a holistic view of intraoperative events. This innovative tool serves…
Ultrasound-guided ablation techniques, particularly radiofrequency ablation (RFA), show effectiveness in treating benign thyroid nodules. RFA with 2 sessions is optimal for solid nodules, while polidocanol ablation stands out for cystic nodules. A network meta-analysis of 35 studies involving 5655 patients demonstrated RFA as the most…
Higher hospital surgical volume correlates with significantly better short- and long-term outcomes after rectal cancer surgery. Patients treated in hospitals with higher surgical volume experienced lower 90-day and 1-year excess postoperative mortality rates and higher 5-year observed survival rates compared to those treated in lower-volume…
Laparoscopic lavage for non-feculent perforated diverticulitis shows lower mortality, shorter hospital stays, and fewer subsequent surgeries, compared to sigmoid resection. It is a safe alternative for select patients, especially those younger, healthier, and with less previous abdominal surgeries. Laparoscopic lavage offers promising outcomes as a…
Improved systemic therapy has increased long-term survival rates after resection of pancreatic ductal adenocarcinoma. Sex, BMI, tumor markers, and pathological characteristics influence long-term survival. No single factor can predict survival, highlighting the complex interplay between risk, biology, and patient management. A systematic review analyzing 25…
In laparoscopic subtotal gastrectomy for gastric cancer, utilizing indocyanine green (ICG) fluorescence for lymph node dissection significantly enhances metastasis detection, with a sensitivity of 75.86% and a high negative predictive value of 97%. The method effectively visualizes lymph nodes, aiding in clinically radical gastrectomy, suggesting…
Triclosan-coated sutures significantly reduce the incidence of surgical site infections (SSI) after abdominal surgery by 2%, as demonstrated in a meta-analysis of 11 randomized controlled trials with over 10,000 patients. This study found lower SSI rates in the triclosan-coated group compared to uncoated sutures, particularly…
