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General Surgery

Best Papers in General Surgery

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Int J Surg4 May 2024

Global Trends in Early-Onset Pancreatic Cancer: A 30-Year Analysis

Early-onset pancreatic cancer (EOPC) is increasing globally, particularly in Asia, with high burden in central and eastern Europe. From 1990 to 2019, EOPC saw a rise in incidence, mortality, and disability-adjusted life-years (DALYs). Risk factors include smoking, high BMI, and high glucose levels. Prevention strategies…

Int J Surg4 May 2024

Predicting Overall Survival in GEP-NETs Using a Treatment Data Nomogram

A nomogram incorporating treatment data proved better than the AJCC staging system in predicting overall survival for gastroenteropancreatic neuroendocrine tumors. Key factors include sex, age, race, tumor location, and treatment modalities. Internal and external validation showed superior performance, advocating for individual risk evaluation to enhance…

Upper Gastrointestinal Tract4 May 2024

Advancements in Minimally Invasive Surgical Techniques for Early Gastric Cancer

Minimally invasive surgical techniques, such as endoscopic mucosal resection and laparoscopic and endoscopic cooperative surgery, offer precise and effective options for treating early gastric cancer. These advanced procedures result in less trauma, blood loss, and quicker recovery for patients, providing unique value in the examination…

Gastrointest Endosc3 May 2024

Direct Percutaneous Endoscopic Jejunostomy Tube Placement: A Safer Alternative

Direct percutaneous endoscopic jejunostomy (DPEJ) is a safe and effective alternative to surgical jejunostomy, with lower rates of adverse events at 90 days. Procedural success rates were similar among DPEJ, laparoscopic jejunostomy, and open jejunostomy, but DPEJ had significantly lower rates of tube dysfunction. DPEJ…

JAMA Surg3 May 2024

Incisional Wound Irrigation with Antiseptic Solutions Reduces Surgical Site Infections

Researchers found that using antiseptic solutions for prophylactic intraoperative incisional wound irrigation significantly reduced surgical site infections (SSIs). In this systematic review and network meta-analysis involving 41 randomized clinical trials with 17,188 patients, antiseptic solutions showed a 40% relative risk reduction in SSIs compared to…

Appendix, Gallbladder and Surgical Emergencies3 May 2024

Interval Appendectomy After Antibiotic Treatment for Appendicitis: Is It Necessary?

Researchers discuss the pros and cons of interval appendectomy for patients who have recovered from acute uncomplicated appendicitis after successful antibiotic treatment. Although surgery has traditionally been the standard treatment, recent data suggest that antibiotics are a safe alternative. However, the high rate of recurrent…

Appendix, Gallbladder and Surgical Emergencies3 May 2024

Reevaluating Interval Appendectomy After Successful Antibiotic Treatment for Appendicitis

Clinicians debate the merits of interval appendectomy for patients who recover from antibiotic treatment for acute uncomplicated appendicitis. Offering this surgery to avoid future appendicitis risks extra costs, disability, and potential complications, even though many patients may never need surgery. Major clinical trials show high…