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General Surgery

Best Papers in General Surgery

The five that matter, every day.

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HPB & Spleen27 Apr 2024

Advancements in Medical Treatment for Pancreatic Neuroendocrine Tumors

This editorial highlights remarkable advancements in tailored medical treatment strategies for pancreatic neuroendocrine tumors. Cytoreductive surgery and somatostatin analogs are key in managing tumors, with additional treatment options available for refractory patients. Different subtypes require distinct therapeutic approaches, and ongoing research on the genetic basis…

Sarcoma & rare tumors27 Apr 2024

High recurrence rates in ischiorectal fossa tumors despite surgical resection

An analysis of 34 cases of ischiorectal fossa tumors over a 30-year period found a high recurrence rate, with 35% of patients experiencing recurrence even after R0 resection. The median follow-up was 23 months, and the median time to recurrence was 6.5 months. Although there…

Surg Endosc27 Apr 2024

Advanced Laparoscopic Hepatectomy Safety in Elderly Japanese Patients

Advanced laparoscopic hepatectomy in elderly Japanese patients showed similar or better safety compared to open hepatectomy, with lower mortality rates, reduced blood product use, and shorter hospital stays. The study highlights the feasibility and safety of advanced laparoscopic hepatectomy in elderly patients, supporting its use…

Surg Endosc27 Apr 2024

Comparative Analysis of Hemostatic Products for Surgical Hemostasis

A review of commercially available hemostatic agents in the US provides a comprehensive guide for general surgeons. The paper summarizes each product's mechanism of action, indications, contraindications, best-use cases, and expected results. Hemostatic agents are critical adjuncts for minimizing postoperative bleeding risks, and proper education…

Surg Endosc27 Apr 2024

Optimal Management of Hiatal Hernia

A systematic review and meta-analysis of 45 studies on hiatal hernia management, including data from randomized controlled trials and observational studies, found that the use of mesh was associated with a lower recurrence risk (RR = 0.50, 95% CI 0.28, 0.88). Despite the overall high…

J Am Coll Surg26 Apr 2024

Improving Adrenal Incidentaloma Evaluation Through a Quality Improvement Initiative

Implementation of a quality improvement program led to increased primary care provider-initiated evaluation of adrenal incidentalomas, with 35.5% meeting the primary endpoint in the quality improvement cohort compared to 27.6% in the historical cohort. Patients in the quality improvement cohort had 1.70 times higher odds…

J Am Coll Surg26 Apr 2024

Improving Adrenal Incidentaloma Evaluation Through a Quality Improvement Initiative

Implementation of a quality improvement program led to increased primary care provider-initiated evaluation of adrenal incidentalomas, with 35.5% meeting the primary endpoint in the quality improvement cohort compared to 27.6% in the historical cohort. Patients in the quality improvement cohort had 1.70 times higher odds…

Ann Surg Oncol26 Apr 2024

Improved Detection of Residual Peritoneal Metastases with Pegsitacianine Imaging Agent

Use of pegsitacianine, a pH-sensitive imaging agent, detected residual disease in 50% of patients undergoing cytoreductive surgery. Pegsitacianine showed high sensitivity, improved surgeon assessment, and had acceptable safety profile. This agent has the potential to enhance detection of residual disease and improve outcomes in peritoneal…

Ann Surg Oncol26 Apr 2024

Improved Detection of Residual Peritoneal Metastases with Pegsitacianine Imaging Agent

Use of pegsitacianine, a pH-sensitive imaging agent, detected residual disease in 50% of patients undergoing cytoreductive surgery. Pegsitacianine showed high sensitivity, improved surgeon assessment, and had acceptable safety profile. This agent has the potential to enhance detection of residual disease and improve outcomes in peritoneal…

BMC Surg26 Apr 2024

Clinical Characteristics and Outcomes of Adrenal Hemorrhage

Adrenal hemorrhage, often triggered by trauma, presents diverse clinical manifestations. A retrospective analysis of 193 cases revealed a majority of unilateral hemorrhages, with trauma as the leading cause. Notably, many adrenal nodules went undetected initially, underscoring the importance of thorough evaluation. Follow-up imaging demonstrated varied…