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Best Papers in General Surgery
The five that matter, every day.
Prolonged acid reflux monitoring for 96 hours diagnosed more patients with GERD compared to standard 48-hour testing. Extended monitoring led to clinically significant changes in study interpretation, with almost half of patients showing abnormal results after a normal study on day 1. Results suggest that…
Patients aged 75 and older have significantly higher rates of perioperative complications after elective ventral or incisional hernia repair compared to younger patients. A retrospective cohort study of 116,643 patients showed that older age was associated with increased risk of post-operative complications, readmissions, extended hospital…
Patients with resectable pancreatic cancer were randomized to receive either adjuvant gemcitabine or perioperative FOLFIRINOX. Perioperative FOLFIRINOX led to almost doubled median progression-free survival compared to adjuvant gemcitabine in patients who underwent surgical resection. Despite premature trial termination due to poor accrual, perioperative FOLFIRINOX showed…
One in ten patients with pancreatic ductal adenocarcinoma experiences very early recurrence after surgery (classified as biological R2), necessitating routine imaging within 12 weeks. Body-tail site lesion was the only preoperative predictor, with higher pt, g3 differentiation, and high lymph node ratio as pathological predictors.…
Textbook outcome (TO) was achieved in one-third of patients after pancreatoduodenectomy (PD) for nonfunctioning pancreatic neuroendocrine tumors (NF-PANNETs). Tumor size, minimally invasive approach, and surgical volume were predictors of TO. TO was not associated with improved long-term survival, with similar rates seen in patients with…
Preoperative imaging based on the probability of having adenomas can significantly reduce unnecessary bilateral neck explorations in patients undergoing parathyroidectomy. Adenomas were associated with higher calcium and parathyroid hormone levels compared to hyperplasia. The likelihood that imaging helped with operative planning increased with the predicted…
Large language models (LLMs) like GPT-4 significantly improve the readability of bariatric surgery patient education materials (PEMs), with responses ranging from 6th to 9th grade reading levels. While GPT-3.5 and GPT-4 showed similar accuracy and comprehensiveness in simplifying responses, Bard's responses were less comprehensive when…
Combat casualties requiring emergent laparotomy have a mortality rate of 29.5%, compared to 6.5% in normotensive patients. Despite implementing damage control principles, mortality rates remained high in hypotensive patients. The study analyzed 1051 patients, showing no improvement in hypotensive casualty mortality rates after the implementation…
Analysis of worldwide IFSO survey on metabolic and bariatric surgery (MBS) indicates that 74.6% of national societies have MBS guidelines, with 34% adopting the latest ASMBS/IFSO 2022 guidelines. However, 22% still follow outdated NIH 1991 recommendations. Financial coverage for MBS is present in 65% of…
Researchers developed and validated a novel Difficulty Score System for robotic hepatectomy based on 274 patients. Factors such as neoadjuvant chemotherapy, tumor characteristics, extent of resection, and additional procedures were associated with operative time and blood loss, resulting in difficulty scores ranging from 1 to…
