After bariatric surgery, attention capacity and executive function improved, while immediate memory worsened. Serine, glutamic acid, and glycolic acid were identified as potential metabolites linked to cognitive performance alterations. Cluster analysis revealed two subgroups, with cluster 2 showing improved attention and executive function but reduced immediate memory. These findings suggest that bariatric surgery affects cognitive […]
Category: General Surgery
Esophageal Washout with Povidone-Iodine Reduces Intraluminal Tumor Cells in Carcinoma Resection
Intraoperative esophageal washout with povidone-iodine solution significantly reduces the presence of free intraluminal tumor cells during esophageal and cardiac carcinoma resection. Neoadjuvant treatment decreases the likelihood of malignant cells in the esophagus. Repetitive washout decreases detectable malignant cells, with a significant reduction after 10 maneuvers. This novel, feasible procedure can help eliminate tumor cells and […]
Deficiencies in Reporting Clinical Significance in Contemporary CER
Contemporary Comparative Effectiveness Research (CER) often lacks explicit specification of clinically significant differences in study outcomes, as revealed in a systematic review of 307 studies from prominent medical journals. Only 8.5% of studies specified clinical significance, with 2.3% recommending changes in clinical decision-making based on statistical significance alone. Authors frequently defined clinical significance using validated […]
ICG-Guided Lymphadenectomy in LAGC: RCT Results
Indocyanine Green (ICG)-guided lymph node (LN) dissection during laparoscopic radical gastrectomy significantly improves the quality of lymphadenectomy in locally advanced gastric cancer (LAGC) patients post-neoadjuvant chemotherapy (NAC). A randomized controlled trial with 236 patients demonstrates that ICG increases LN retrieval and decreases non-compliance rates, particularly in cases without baseline measurable LNs and in those with […]
PORSHA for Paraesophageal Hernias: Phase 2a Results
Posterior Rectus Sheath Hiatal Flap Augmentation (PORSHA) exhibits promise as a surgical innovation for large and recurrent paraesophageal hernias. In a study of 27 cases, PORSHA, after technical modifications, demonstrated safety and success in repairing type III, IV, and recurrent paraesophageal hernias. At an 11-month follow-up, there were no radiologic recurrences, abdominal eventrations, or hernias […]
Pediatric Pancreatic Surgery: Safe, Effective, and Centralized
Pediatric pancreatic surgery, analyzed in a 73-patient study, demonstrated safety and effectiveness. Distal pancreatectomy was the most common procedure, addressing indications like chronic pancreatitis, tumors, and trauma. Postoperative morbidity occurred in 34.2%, with no 90-day mortality. The 5-year overall survival was 90.5%, emphasizing the feasibility of pediatric pancreatic surgery. Centralization in specialized pancreatic centers ensures […]
Crucial Role of EUS in LT Workup for Unresectable pCCA
EUS plays a crucial role in the liver transplantation (LT) workup for patients with unresectable perihilar cholangiocarcinoma (pCCA). In a nationwide study, EUS identified malignant nonregional lymph nodes (LNs) in 4% of patients potentially eligible for LT. Surgical staging confirmed malignancy in 14% of patients with nonregional LNs. The study emphasizes the limited but clinically […]
Patient Engagement Technologies in Colorectal Surgery: Improving Outcomes Through Interaction
Patients engaging with patient engagement technologies (PETs) during colorectal surgery showed improved outcomes. In a retrospective study, 89.1% activated PETs, completing surveys and health-checks. Those engaging more frequently experienced shorter lengths of stay, lower readmission rates, and fewer post-operative complications. Notably, patients who completed more post-discharge health-checks had a lower complication rate, emphasizing the positive […]
TSLG versus LTH for Siewert Type II AEG: Advantages and Efficacy
Transthoracic single-port-assisted laparoscopic gastrectomy (TSLG) demonstrates technical safety and feasibility in comparison to laparoscopic transhiatal approach (LTH) for Siewert type II adenocarcinoma of the esophagogastric junction. In a retrospective study, TSLG showed advantages, including increased harvested lymph nodes, reduced lower mediastinal lymph nodes, and longer proximal margins. The R0 gastrectomy rate was higher in the […]
Single Anastomosis Duodeno-Ileal Bypass (SADI-S) Shows Comparable Outcomes in Primary and Two-Stage Approaches
Comparing outcomes of primary single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) to two-stage SADI-S after sleeve gastrectomy (SG), a Canadian bariatric study with 179 laparoscopically treated patients (2016–2020) revealed both approaches as efficient in achieving weight loss and comorbidity reduction at short and mid-term follow-ups. Preoperative criteria are crucial for surgeon decision-making between primary […]