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Best Papers in General Surgery
The five that matter, every day.
Researchers developed a preoperative risk score based on early recurrence to estimate outcomes after liver resection in non-cirrhotic hepatocellular carcinoma patients. By analyzing data from 263 patients, they identified macroscopic vascular invasion, multifocal tumor, and spontaneous tumor rupture as predictors of early recurrence. This score…
Researchers conducted a study on 63 morbidly obese patients undergoing laparoscopic sleeve gastrectomy to determine the optimal percentage of excised stomach for significant weight loss and improvement in fatty liver. They found that a %rgv value of >75.3% led to more significant weight loss, while…
Researchers investigated perioperative factors influencing survival in pancreatic ductal adenocarcinoma (PDAC) surgery. Analyzing a Danish cohort (2011–2020), they found that perioperative blood transfusions were linked to significantly shorter overall survival (OS) in resected PDAC patients (HR 2.53, p = 0.005), with a marked difference at 72 months…
Researchers analysed 338 cyst fluid samples from 190 IPMN patients and found no significant difference in microbiome signatures compared to negative controls. In patients who recently had invasive procedures, a gut-associated microbe outlier signal was evident. The study concluded that IPMNs and pancreatic cystic neoplasms…
Laparoscopic HIPEC for gastric cancer with peritoneal metastasis is safe and associated with minimal perioperative complications. Approximately one third of patients undergoing initial laparoscopic HIPEC proceeded to cytoreduction and gastrectomy. Preliminary survival data from this study indicate a median overall survival of 11 months from…
Complete liver splitting along the demarcation line induced higher portal vein pressure and more rapid future liver remnant hypertrophy than partial or ectopic liver splitting after portal vein ligation in a rat model. The portal hemodynamic alterations, rather than inflammatory cytokine release, played a significant…
Rectal cancer survivors with low anterior resection syndrome showed improvement beyond 3 years post-proctectomy, with a decrease in mean syndrome score from 29.5 to 18.6. 31.5% experienced a shift from major to no/minor severity, while 3.4% required a new stoma. Long-term improvement was negatively associated…
Preoperative biliary obstruction and operation time were identified as significant risk factors for postoperative infection in choledochoscopy for intrahepatic bile duct stones. Biliary tract infections, particularly with Escherichia coli, were the main cause of postoperative infection. Biliary tract obstruction and body mass index were independent…
Assessment of intraoperative adverse events (IAEs) during robotic radical gastrectomy for gastric cancer revealed that IAEs significantly correlated with postoperative complications and poor long-term prognosis. The presence of IAEs was associated with worse overall and disease-free survival rates compared to patients without IAEs. Utilizing the…
The study compared perioperative complications, quality of life, and functional outcomes in patients with ulcerative colitis undergoing either 3-stage or modified 2-stage IPAA. Results showed similar rates of anastomotic leak, surgical site infection, ileus, quality of life, and pouch function between the two approaches. However,…
