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Best Papers in General Surgery
The five that matter, every day.
Comparing outcomes of primary single anastomosis duodeno-ileal bypass with sleeve gastrectomy (SADI-S) to two-stage SADI-S after sleeve gastrectomy (SG), a Canadian bariatric study with 179 laparoscopically treated patients (2016–2020) revealed both approaches as efficient in achieving weight loss and comorbidity reduction at short and mid-term…
In a cross-sectional study analyzing data from 152 German and Austrian hospitals, researchers determined procedure-specific, risk-adjusted probabilities of postoperative nausea for 72 types of operations. The adjusted absolute risk ranged from 6.2% to 36.2%, with laparoscopic bariatric operations having the highest risk. Factors such as…
In cholecystectomy patients with small common bile duct stones (≤5 mm) identified by intraoperative ultrasound, a short-term expectant management approach, avoiding immediate duct clearance, proved safe. Among 51 patients, 46 underwent expectant management, with 89.1% not requiring postoperative interventions. Over 3 years, none presented with…
Ki-67 proliferation index was found to be associated with tumor grade in pleural epithelioid mesotheliomas, showing comparable predictability for overall survival to mitotic score. High Ki-67 index and mitoses were significantly linked to poor overall survival, suggesting that Ki-67 index by digital image analysis could…
Compared to upfront surgery, neoadjuvant chemotherapy for locally advanced colon cancer is associated with lower recurrence and mortality hazards, higher 5-year survival rates, and increased disease-free survival rates. Additionally, it reduces the risk of incomplete resection without significantly impacting perioperative complications or mortality. These findings…
Endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS) is associated with higher rates of adverse events and recurrent biliary obstruction compared to antegrade stenting followed by EUS-HGS (EUS-HGAS) in patients with malignant distal biliary obstruction. However, EUS-HGAS significantly extends the time to recurrent biliary obstruction, potentially benefiting patients with…
Recurrence-free survival is a valid surrogate endpoint for overall survival in surgically resectable advanced oesophageal squamous cell carcinoma (oscc) patients receiving neoadjuvant chemotherapy. A strong correlation (kendall's τ 0.797) was found between the two endpoints, particularly in patients with a more favorable response to neoadjuvant…
Wound irrigation with polyhexanide solution did not significantly decrease the incidence of surgical site infections compared to saline or no irrigation after laparotomies. The study, involving 689 patients, found an overall infection rate of 11.8%, with no statistically significant difference between the groups. Further research…
Researchers evaluated total neoadjuvant therapy with immunotherapy for high-risk rectal cancer with proficient mismatch repair status. The study showed a pathologic complete response rate of 33.3%, with 48% achieving clinical complete response. R0 resection was achieved in all patients. Adverse effects were manageable, with nausea…
After analyzing 200 measurements from 100 patients undergoing posterior component separation with transversus abdominis release, researchers found that baseline and residual abdominal wall tensions did not affect early postoperative complications such as surgical site infection, readmission, ileus, and bleeding. Further investigation is required to determine…
