Recurrence after surgery for colorectal liver metastases (CRLM) is common within two years, but there is no established guidance on follow-up methods and intensity. A systematic review of 25 articles involving 9,945 patients revealed wide variation in follow-up methods, with CT as the most common imaging modality and CEA as the most common blood test. […]
Category: General Surgery
Long-Course Chemoradiotherapy Outperforms Short-Course Radiotherapy in Locally Advanced Rectal Cancer
The study compared the oncological outcomes of long-course chemoradiotherapy (LC-CRT) and short-course radiotherapy with delayed surgery (SCRT-delay) in locally advanced rectal cancer (LARC) patients. The results showed that LC-CRT had higher overall survival (OS) rates at 1, 3, and 5 years compared to SCRT-delay. Additionally, LC-CRT group had higher cancer-specific survival (CSS) rates at 1, […]
Big Data Analysis Reveals Hiatus Hernia’s Link to Esophageal Disorders
Researchers conducted a comprehensive analysis using big data to investigate the frequency of hiatus hernia (hh) and its association with esophageal disorders. They reviewed endoscopic reports of over 75,000 patients and found that hh was present in 16.8% of cases, with the majority being small hhs. They also found that hh was significantly associated with […]
Structured follow-up after resection for biliary tract cancer improves overall survival
A retrospective multicenter cohort study compared two follow-up strategies for patients after curative resection of biliary tract cancer. The study found that structured follow-up resulted in more patients receiving palliative therapy after recurrence compared to pragmatic follow-up. Additionally, the median overall survival was significantly lower in the pragmatic group. However, patients who actually received chemotherapy […]
Advanced Surgical Treatment of Pancreatic Ductal Adenocarcinoma: Current Challenges and Opportunities
Recent advancements in chemo/radiotherapy have rendered previously inoperable patients with pancreatic ductal adenocarcinoma (PDAC) potentially resectable. This narrative review highlights the current state of surgical treatment for borderline resectable, locally advanced, and synchronous or metachronous oligometastatic PDAC. Neoadjuvant therapy (NAT) is recommended before surgery, although the best response rate is still limited. Methods for selecting […]
Individualized Age Cessation in IPMN Surveillance: A Cost-Effectiveness Analysis
Researchers conducted a simulation study to determine the optimal age to discontinue long-term surveillance of low-risk intraductal papillary mucinous neoplasms (IPMNs). Using a markov model and clinical cohort data, they calculated the cost-effectiveness of continued versus discontinued surveillance at different ages. They found that the optimal age to stop surveillance varied based on sex and […]
Indocyanine Green-Guided Laparoscopic RLPS: Safe and Feasible for Synchronous Liver Metastases
Laparoscopic right posterior sectionectomy (RLPS) with an extrahepatic Glissonian approach and modified hanging maneuver, guided by indocyanine green fluorescence imaging, proves safe and feasible for a patient with mid-rectum adenocarcinoma and synchronous liver metastases. The procedure involves selective clamping, indocyanine green injection, and precise parenchymal transection along a marked plane. Detaching a metastasis from the […]
Laparoscopic Portal Vein Ligation and Embolization Facilitate Safe Second Hepatectomy for Unresectable Colorectal Liver Metastases
Laparoscopic two-stage hepatectomy with portal vein embolization ensures safe completion of surgery for initially unresectable colorectal liver metastases. Three patients received chemotherapy followed by laparoscopic colorectal resection and limited hepatectomies. After right portal vein ligation, laparoscopic portal vein embolization using ethanol facilitated the second hepatectomy. No postoperative complications occurred in six surgeries, suggesting the safety […]
Adjuvant Therapy Trends Post Resection in Pancreatic Cancer
Approximately 25.2% of pancreatic cancer patients who underwent upfront resection did not receive adjuvant therapy (AT), according to a prospective observational study. The main reasons for AT omission were postoperative complications, oncologist’s choice, baseline comorbidities, patient’s choice, and early recurrence. Older age, comorbidities, and postoperative complications were the main factors associated with AT omission. Additionally, […]
Transoral thyroidectomy associated with higher postoperative pain levels compared to conventional thyroidectomy
The study compared postoperative pain levels between transoral and conventional transcervical thyroidectomy. After matching patients based on six covariates, the transoral group had higher pain scores than the conventional group from day 1 to day 6 post-surgery, with no significant difference at 1 month. Among transoral procedures, the endoscopic approach had significantly higher pain scores […]