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Best Papers in General Surgery
The five that matter, every day.
A retrospective cohort study was conducted to assess the local recurrence and survival rates after transanal abdominal transanal radical proctosigmoidectomy for low rectal cancer treated with neoadjuvant chemoradiation therapy. The study included 255 patients and found that the procedure demonstrated excellent long-term locoregional control and…
This study aimed to determine the incidence and risk factors of hyperthyroidism after parathyroidectomy. In a prospective study of 91 patients, 24.2% had suppressed thyroid-stimulating hormone (TSH) after the procedure, with 2.2% reporting symptoms of hyperthyroidism. However, all cases resolved within 6 weeks without medical…
Researchers analyzed data from patients who underwent complex hepato-pancreato-biliary surgeries in Uganda, reporting that most patients were females with a median age of 50 years. The most common surgeries performed were on the bile ducts, with a high prevalence of malignancy. Despite challenges like limited…
Rectal cancer patients who underwent Hartmann's procedure were significantly older, had more comorbidities, and were more likely to have the procedure preoperatively due to comorbidities or oncological reasons. In 23% of cases, the decision to perform Hartmann's procedure was made intraoperatively, mainly due to anastomotic…
Journal Article by Abbassi F, Pfister M (...) Clavien PA et 2 al. in Ann Surg
Patients' perspectives on colectomy for recurrent diverticulitis were explored through focus groups. A conceptual framework was developed to capture major themes identified in the qualitative data. The study found that the decision to pursue colectomy is highly preference sensitive, influenced by patients' beliefs about surgery,…
A comprehensive cohort study of 4,301 patients undergoing antireflux and hiatus hernia surgeries in Australia revealed a 12.6% incidence of intraoperative complications and a 13.3% incidence of postoperative complications. Independent predictors of complications included the Charlson comorbidity index, hernia size, revisional surgery, and baseline anticoagulant…
This study aimed to identify potential biomarkers for early prediction of persistent organ failure (POF) in acute pancreatitis (AP) patients. Using serum exosomal miRNAs, researchers identified a classifier comprising three miRNAs (miR-4265, 1208, 3127-5p) that demonstrated high predictive value for POF. This classifier outperformed other…
Continuous wound irrigation and intraoperative methadone usage in cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) significantly reduced opioid use and shortened length of hospital stay compared to epidural analgesia. The combination of continuous wound infusion system (CWIS) and methadone resulted in lower total and daily…
The field of coloproctology is witnessing a paradigm shift towards less invasive treatments due to remarkable advancements in medical care. This shift is particularly notable in gastroenterology, specifically in colorectal surgery. Both benign and malignant colorectal conditions are now being treated with more conservative and…
