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Best Papers in General Surgery
The five that matter, every day.
Researchers analyzed local recurrence and disease-free survival in patients treated with transanal total mesorectal excision (TaTME) for rectal cancer. The study included 279 patients treated at a high-volume tertiary center in Vancouver, Canada. The results showed that the local recurrence rate was 4.7%, and the…
A study investigated the utility of machine learning algorithms in predicting complications for patients undergoing colectomy for colonic neoplasia. The three machine learning models successfully identified patients who developed complications, with the neural network scoring highest in predicting anastomotic leak, prolonged length of stay, and…
Internal orifice narrowing achieved by suturing the distal hernia sac in laparoscopic repair of inguinoscrotal hernias significantly reduces the incidence and volume of seroma formation. A double-blind randomized controlled trial with 58 patients showed a lower seroma incidence at 7 days and reduced seroma volume…
The study analyzed the risks and consequences of failed nonoperative management of appendicitis in older adults. Using data from the 2004-2017 national inpatient sample, the researchers found that nonoperative failure in patients under 65 was associated with increased morbidity, length of stay, costs, and discharges…
Analysis of the MAUDE database reveals that the single operator cholangioscopy (SOC) system, specifically the SpyGlass DS and DS II devices, carries additional risks compared to standard endoscopic retrograde cholangiopancreatography. The study identifies 2,331 device problems reported between January 2016 and August 2023, with optical…
Elevated levels of CA 19-9, a tumor marker, were found to be associated with decreased progression-free survival (PFS) in patients with colorectal peritoneal metastases (CRPM) treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC). The study, which included 279 patients, showed that patients with elevated…
The study compared long-term oncologic outcomes of robotic and laparoscopic surgeries in rectal cancer patients who underwent neoadjuvant chemoradiotherapy (NCRT) followed by radical resection. After propensity score matching, the robotic group demonstrated higher 5-year disease-free survival and local recurrence-free survival rates compared to the laparoscopic…
Among patients with initially unresectable hepatocellular carcinoma (uhcc), combination therapy with transcatheter arterial chemoembolization, lenvatinib, and anti-PD-1 antibodies achieved high tumor response rates and converted some cases to resectable disease. A retrospective study compared outcomes in uhcc patients who underwent salvage surgery (sr group) versus…
A study investigated the use of a fut variant-based CA19-9 tumor marker gene test to assess the outcome of pancreatic cancer surgery. The test showed that higher preoperative CA19-9 levels were associated with recurrence and mortality in patients with higher fut groups, but not in…
Myosteatosis and creatinine-to-cystatin C ratio (CCR) were evaluated as prognostic biomarkers in patients with pancreatic cancer (PC) who underwent radical surgery. The study included 215 patients, and the results showed that myosteatosis and CCR ≤ 1.09 were independent risk factors associated with poor overall survival…
