Despite the challenges posed by the COVID-19 pandemic, a retrospective study of 7436 patients undergoing surgery found no evidence of increased 30-day mortality or morbidity during the pandemic surges compared to non-surge periods. Surgical care was successfully maintained, suggesting that healthcare systems effectively adapted to the challenges. The study analyzed data from the American College […]
Category: General Surgery
Extended Chemoprophylaxis Reduces Portomesenteric Vein Thrombosis Rates but Increases Postoperative Bleeding in Laparoscopic Sleeve Gastrectomy Patients
Routine extended (30 days) chemoprophylaxis for laparoscopic sleeve gastrectomy (SG) may decrease portomesenteric vein thrombosis (PMVT) rates. A study of 8,864 SG patients revealed that implementing routine extended chemoprophylaxis significantly reduced PMVT occurrences, but at the cost of a higher postoperative bleeding rate. The majority of increased bleeds were delayed and managed non-operatively. Journal Article […]
Significant advancements in prevention, detection, and treatment have led to an increase in the survival rate of colorectal cancer
Colorectal cancer, a common neoplasm, is increasing in developing countries due to the adoption of Western dietary and lifestyle habits. However, mortality rates have been decreasing in countries with effective prevention and treatment strategies. Routine screenings, improved imaging techniques, surgical advancements, and advancements in chemotherapy and radiation have contributed to earlier detection, accurate staging, and […]
Early Onset Pancreatic Cancer Burden Increasing Worldwide, Especially in Asia and Eastern Europe
Early-onset pancreatic cancer (EOPC) in younger populations is characterized by poor differentiation and is increasing globally. According to the Global Burden of Disease Study, there were 36,852 new cases and 32,004 deaths from EOPC in 2019. East Asia had the highest number of cases, while Central and Eastern Europe had notably high burden. Incidence, mortality, […]
Body fat mass loss after radical resection for pancreatic ductal adenocarcinoma predicts poor prognosis
Body fat mass loss was analyzed in patients undergoing radical resection for pancreatic ductal adenocarcinoma (PDAC) using bioelectrical impedance analysis. The study found that a body fat mass loss of ≥14% one month after surgery was associated with a poor prognosis. Lymph node metastasis and non-adjuvant chemotherapy were also identified as independent poor prognostic factors. […]
Opoid-Free Analgesia Leads to Reduced Pain Severity and Risk of Side Effects After Surgery
Patients receiving opioid-free analgesia after surgery experience lower pain severity and decreased risk of side effects compared to those prescribed opioids, according to a multispecialty, prospective cohort study in 25 countries. The study involved 4273 patients from 144 centers, with 30.7% receiving opioid analgesia at discharge. The findings emphasize the need to routinely adopt opioid-free […]
Frailty Score Correlates with Surgical Outcomes in Optimization Before Surgery
Researchers investigated the correlation between frailty score, pre-surgical optimization, and surgical outcomes in frail patients undergoing optimization before surgery. A retrospective study was conducted on patients referred to the surgical optimization clinic and assessed for frailty, and outcomes were evaluated based on whether they proceeded to surgery or had their surgery cancelled or delayed. The […]
Majority of Variation in Lymph Node Assessment for Colon Cancer Linked to Non-modifiable Tumor Factors
Researchers investigated the factors contributing to variation in lymph node assessment for colon cancer and found that non-modifiable tumor factors were responsible for the majority of variation. A dataset of over 280,000 patient records from 15,000 surgeons across 1,200 facilities was analyzed. The achievement of the 12 lymph node standard was high at 90.3%. Factors […]
Higher 30-day surgical complications observed in Asian Americans after esophagectomy
Asian Americans face higher 30-day surgical complications following esophagectomy compared to Caucasians, according to a retrospective analysis of the ACS-NSQIP database. The study found that Asian Americans had a greater likelihood of pulmonary complications, particularly pneumonia, renal dysfunction, including progressive renal insufficiency, and bleeding events. They also had a longer length of stay. These findings […]
Short-Term Metabolic Improvements Following Roux-en-Y Gastric Bypass
The study investigated the metabolic changes and physiological factors mediating the effects of Roux-en-Y gastric bypass (RYGB) surgery in obese patients. Results showed that insulin concentrations decreased significantly after the surgery, along with improvements in weight loss and insulin sensitivity. Additionally, triglycerides, remnant cholesterol, lactate, glycoprotein acetyls, and certain amino acids decreased post-surgery. The study […]