According to a single-center prospective cohort study, physical activity levels are far from optimal following major abdominal cancer surgery. The study found that postoperative physical activity was low, with a median daily step count ranging from 71 steps on the first postoperative day to 918 steps on the seventh day. Furthermore, the study identified several […]
Category: General Surgery
Frailty Index in Colorectal Cancer: Assessing Surgical Complications and Prognosis
Frailty Index (FI) is a comprehensive tool for assessing frailty in the elderly population with colorectal cancer (CRC). This review evaluates methods for frailty assessment and presents modifications of the FI to accurately evaluate surgical complication risk and prognosis in CRC patients. The research findings highlight the FI’s role in predicting surgical complications, postoperative recovery, […]
A Delayed Diagnosis: Tuberculosis Mimicking Colorectal Malignancy
Gastrointestinal tuberculosis is a rare manifestation that often imitates various gastrointestinal diseases. In this case study of an 85-year-old male patient, a cecal mass initially suspected to be malignant was removed through colonic resection. Acid-fast staining of the surgical specimen later revealed acid-fast bacilli and necrotizing granulomas in multiple lymph nodes. The study highlights the […]
Modified pancreaticoduodenectomy: A viable alternative to hepatopancreaticoduodenectomy for middle-third cholangiocarcinoma
The study compared the outcomes of patients with middle-third cholangiocarcinoma who underwent modified pancreaticoduodenectomy (MPD) or hepatopancreaticoduodenectomy (HPD). The MPD group exhibited advantages such as shorter operation time, less blood loss, and fewer complications compared to the HPD group. Overall survival rates did not significantly differ between the groups. The study identified positive surgical margins […]
aMAP Score Predicts Long-term Outcomes in HCC Resection
A proposed model called the aMAP score was evaluated for its ability to predict long-term outcomes in patients undergoing resection for hepatocellular carcinoma (HCC). The results showed that a high aMAP score was associated with poorer 5-year overall survival (OS) rates compared to a low aMAP score. The aMAP score was also found to be […]
High Resection to Exploration Ratios and Variable Survival Outcomes in Pancreatic Ductal Adenocarcinoma Patients
Researchers conducted a study to investigate resection to exploration ratios (RER) and outcomes in patients with pancreatic ductal adenocarcinoma (PDAC). The overall RER was found to be 89.7%, with higher ratios observed in upfront explorations compared to post-neoadjuvant explorations. The primary reasons for uncompleted resection were occult metastases in presumed resectable/borderline resectable disease and local […]
Long-term Oncological Outcomes of Robotic and Laparoscopic Gastrectomy for Gastric Cancer
The multicentre cohort study aimed to compare the long-term oncological outcomes between robotic gastrectomy (RG) and laparoscopic gastrectomy (LG) for patients with gastric cancer. The study included a total of 2,055 patients who underwent RG and 4,309 patients who underwent LG. After matching the patients using propensity scores, the study found that RG and LG […]
Combining Oncolytic Virus and CD19-CAR-T Cells Shows Promise in Treating Pancreatic Cancer
A study found that combining an oncolytic virus with CD19-Chimeric Antigen Receptor-T (CAR-T) cells was effective in treating pancreatic cancer. The engineered virus successfully infected and expressed CD19 on tumor cells, leading to an increased immune response and cell killing when co-cultured with CD19-CAR-T cells. In combination therapy, the virus and CAR-T cells significantly reduced […]
The Impact of Socioeconomic Deprivation on Access to Guideline-Concordant Treatment in Foregut Cancer
High socioeconomic deprivation, as measured by the area deprivation index (ADI), significantly reduces the likelihood of receiving guideline-concordant treatment (GCT) for foregut cancers. In a retrospective study of 498 patients, 66% received GCT, with lower rates observed in pancreatic, gastric, and hepatobiliary cancers. Factors independently associated with non-receipt of GCT included age ≥75 years, black […]
Active Gas Aspiration Reduces Postoperative Pain in Laparoscopic Cholecystectomy
Active gas aspiration was found to be more effective than passive gas aspiration in reducing postoperative pain and analgesic requirements in patients undergoing laparoscopic cholecystectomy. This systematic review and meta-analysis included 5 randomized clinical trials with 367 participants and found that active gas aspiration resulted in significantly lower residual gas volume and total analgesia requirements. […]