The study aimed to develop a tool to predict the probability of hypocalcemia after total thyroidectomy (TT) by evaluating the percentage decrease in serum parathyroid hormone (PTH) levels in the first 8 hours postoperatively. They prospectively evaluated 97 TT patients, determining the predictors of hypocalcemia requiring calcium supplementation. The results showed that the percentage decrease […]
Category: General Surgery
Frailty Index Successful in Predicting Morbidity in Elective Hernia Repair Patients
Researchers conducted a retrospective analysis using the Modified Frailty Index (MFI) to assess postoperative outcomes in elective hernia repair patients. The study included 14,125 robust patients and 1704 frail patients. Frail patients had higher in-hospital mortality, postoperative morbidity, longer hospital stays, higher healthcare costs, and were less likely to be discharged home. The findings suggest […]
Neoadjuvant GAS Treatment Shows High Efficacy in BRPC-A Pancreatic Cancer: Long-term Phase II Trial Results
The long-term results of a phase II trial evaluating neoadjuvant gemcitabine, nab-paclitaxel, and S1 treatment in borderline resectable pancreatic cancer with arterial contact (BRPC-A) show promising outcomes. Of the 47 patients, 96% underwent pancreatectomy, and the updated median overall survival was 41.0 months with 2- and 5-year survival rates of 68.0% and 44.6%, respectively. Tumor […]
Recurrence Risk in Ampullary Adenomas: FAP vs. Sporadic Cases After Endoscopic Papillectomy
Recurrence rates of ampullary adenomas (AA) after endoscopic papillectomy (EP) were compared between patients with familial adenomatous polyposis (FAP) and sporadic AA. The study included 257 patients from 10 tertiary hospitals. Recurrence occurred in 48% of patients with FAP and 36.9% of patients with sporadic AA. The risk of recurrence was higher in FAP patients […]
Impact of Intraoperative Neural Monitoring on Thyroidectomy Completeness and Thyroglobulin Response in Papillary Thyroid Cancer Patients
In a study evaluating the effect of intraoperative neural monitoring (IONM) during papillary thyroid cancer surgery, researchers found that IONM significantly improved the completeness of thyroidectomy and reduced postoperative levels of stimulated thyroglobulin. Patients who underwent IONM had lower thyroglobulin levels and a higher percentage of patients with levels below 1ng/ml. This information can help […]
Disparities in Emergency General Surgical Procedures for HIV and HCV Patients in the US
People living with HIV (PLWHIV) and people living with hepatitis C virus (PLWHCV) are less likely to receive emergency general surgical procedures (EGS) than similar patients without these conditions. This is the main result of a study analyzing data from over 500,000 non-elective admissions in the United States between 2016 and 2019. Specifically, PLWHIV had […]
Robotic limited liver resections show superior perioperative outcomes compared to laparoscopic limited liver resections for posterosuperior segments
Robotic limited liver resections (RLLR) resulted in superior perioperative outcomes compared to laparoscopic limited liver resections (LLLR) for posterosuperior liver segments, including reduced open conversion rate, blood loss, and operative time. These benefits were observed in both the overall population and in patients with cirrhosis. Postoperative outcomes regarding readmission, morbidity, and mortality were similar between […]
Neoadjuvant Chemotherapy Improves Survival in Resectable Pancreatic Adenocarcinoma Patients
Multiagent neoadjuvant chemotherapy (NAC) followed by surgery is associated with improved overall survival compared to upfront surgery or single-agent NAC in patients with resectable pancreatic adenocarcinoma. A nationwide study conducted on 5,216 patients found that multiagent NAC led to longer median overall survival (35.8 months) compared to upfront surgery (27.1 months) and single-agent NAC (27.4 […]
Procedure-specific Risks of Thrombosis and Bleeding in Abdominal Surgery Vary Significantly
This systematic review and meta-analysis of 285 studies, including over 8 million patients, evaluated the procedure-specific risks of symptomatic venous thromboembolism (VTE) and major bleeding in general abdominal, colorectal, upper gastrointestinal, and hepatopancreatobiliary surgeries. The risk of VTE varied widely among procedures, with VTE rates ranging from
Prognostic Relevance of Primary Tumor Sidedness in Early-stage Colorectal Cancer
The study analyzed data from four randomized controlled trials to determine the significance of primary tumor sidedness (PTS) in early-stage colorectal cancer. The results showed that PTS had no impact on the risk of recurrence in stage II/III colorectal cancer. Treatment stratification based on PTS is unnecessary for early-stage colorectal cancer. However, PTS was significantly […]