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General Surgery

Best Papers in General Surgery

The five that matter, every day.

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JAMA Netw Open11 Feb 2024

Trajectories of Postoperative Depressive Symptoms in Older Surgical Patients

Older adults undergoing major surgery experience distinct trajectories of postoperative depressive symptoms, with three identified groups: sustained low, sustained moderate, and sustained high symptoms. The study, spanning 18 months, reveals that depressive symptoms remained stable for most patients, emphasizing the need for early intervention and…

Int J Surg11 Feb 2024

Metabolic syndrome linked to increased risk of surgical complications

This study reviewed the evidence on the risks of surgical complications in patients with metabolic syndrome (mets) compared to those without mets. The meta-analysis included 63 studies with 1,919,347 patients with mets and 11,248,114 patients without mets. The results revealed that individuals with mets had…

Int J Surg11 Feb 2024

AI’s Pivotal Role in Accelerating Clinical Trials and Medical Breakthroughs

Revolutionizing clinical trials, AI enables expedited and streamlined processes through automated data generation and management. It interprets data, facilitates biosimulation and early disease diagnosis, and reduces costs and time while improving efficiency and drug development research. The study highlights how AI revolutionizes data collection methods…

Ann Surg10 Feb 2024

No Significant Benefit of Goal-Directed Albumin in High-Risk Surgeries

In this randomized clinical trial, researchers investigated whether goal-directed albumin substitution could reduce postoperative complications in high-risk surgery patients. They found that maintaining a serum albumin concentration >30 g/l perioperatively did not significantly reduce the incidence of postoperative complications compared to standard care.

Ann Surg10 Feb 2024

Defining a Framework and Checklist for Sustainable Global Surgical Partnerships

A study aimed to establish a concrete and realistic framework with evaluation metrics to assess sustainability in global surgical partnerships (GSPs) through a modified Delphi technique. Consensus was achieved among 50 global surgery experts from 34 countries, resulting in the development of a 47-item checklist…