Newsletter
Best Papers in General Surgery
The five that matter, every day.
In a retrospective cohort study of 123 patients with intrahepatic cholangiocarcinoma (ICC) who underwent curative surgery, researchers investigated the prognostic value of the Geriatric Nutritional Risk Index (GNRI). Patients with low GNRI scores had significantly poorer outcomes in terms of recurrence-free survival (RFS) and overall…
Machine learning models were developed utilizing pretreatment magnetic resonance imaging (MRI) radiomics and clinical parameters to predict neoadjuvant chemoradiotherapy response in patients with locally advanced rectal carcinoma. The impact of radiomics dimensionality on predictive performance was assessed. Two models were constructed, revealing moderately advantageous effects…
Among 97 patients with non-curative endoscopic resection (ER) for esophageal squamous cell carcinoma (ESCC), 73 underwent additional chemoradiotherapy (CRT). With a median follow-up of 71 months, recurrences were observed in 14% of patients. Lymphatic invasion was identified as an independent risk factor for recurrence. Notably,…
The main result of this study is that preoperative and postoperative serum CA19-9 values are independent risk factors for predicting the prognosis in patients with stage III gastric cancer after curative gastrectomy. Patients with CA19-9 levels greater than 35 U/ml had significantly lower recurrence-free survival…
Neoadjuvant and adjuvant therapy for biliary tract cancer (BTC) have shown limited success in improving outcomes for patients. This review highlights that while a minority of BTC patients are eligible for curative surgery, their survival rates remain poor with high recurrence rates. The study evaluates…
The study assessed the association between surgical volume and patient outcomes in ambulatory surgery centers (ASCs). It found that patients who had surgery at low-volume ASCs had a higher odds of revisiting within 7 days compared to those at higher-volume ASCs. This association was more…
Selective lateral pelvic lymph node dissection after preoperative chemoradiotherapy has been found to decrease local recurrence in middle/low rectal cancer, providing survival benefits. The study investigated the safety, indications, and survival benefits of this procedure based on preoperative characteristics. Results showed that surgery times were…
Sodium thiosulfate can effectively prevent cisplatin-induced nephrotoxicity in patients undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC), eliminating the need for preoperative intravenous hyperhydration. A retrospective analysis of 220 patients showed that the use of sodium thiosulfate significantly reduced serum creatinine levels and preserved glomerular…
Non-Thermal Plasma (NTP) therapy was evaluated as a method to speed up wound healing in patients who underwent laparoscopic and open abdominal surgeries. Researchers used a needle-type reactor with an irradiance of 0.5 w/cm² to apply NTP. The pilot study showed promising results, indicating that…
Despite the involvement of major arteries in pancreatic cancer, pancreatectomy with arterial resection (AR) following neoadjuvant therapy (NAT) can potentially enhance survival rates. A systematic review and meta-analysis of nine retrospective studies, with a total sample size of 215, showed that pancreatectomy with AR achieved…
