The study evaluated the utilization and outcomes of endoscopic retrograde cholangiopancreatography (ERCP) procedures in the first advanced endoscopy center in Palestine. A total of 1909 procedures on 1303 patients were included, with an overall complication rate of 5%. The primary adverse events were post-ERCP pancreatitis (2.3%), infection/cholangitis (1%), bleeding (0.5%), and perforation (0.4%). Risk factors […]
Category: General Surgery
Defecation Symptoms Reflect Dyssynergic Pattern in Constipated Patients
Researchers analyzed retrospective data from high-resolution anorectal manometry and patient-completed bowel habit and symptom diaries to evaluate the usefulness of the diary as a screening tool for disordered rectoanal coordination (DRC). They found that patients with a dyssynergic pattern (DP) during manometry had a higher prevalence of incomplete evacuation with loose or normal stool compared […]
Rising HCC Hospitalizations and Decreased Mortality Highlight Financial Burden
The study analyzed trends in hospitalizations for hepatocellular carcinoma (HCC) in the United States between 2011 and 2017. The researchers found an increase in HCC-related admissions over the years, with a decrease in inpatient mortality rates. However, there was a significant rise in the financial burden on healthcare due to increasing hospital charges and longer […]
Study Finds Similar Mutation Rates in Racial Differences of Stage IV Colorectal Cancer Patients
A retrospective cohort study analyzed molecular profiling and mutation rates in stage IV colorectal cancer (CRC) patients. The study found significant increases in molecular testing rates for microsatellite instability (MSI), KRAS, and BRAF mutations over time. Black patients had higher odds of testing for MSI and BRAF mutations compared to white patients. However, there was […]
Intraoperative Parathyroid Hormone Monitoring Predicts Successful Treatment of Parathyroid Carcinoma
A retrospective review of 796 patients undergoing parathyroidectomy with intraoperative parathyroid hormone (iPTH) monitoring for primary hyperparathyroidism identified 18 patients with parathyroid carcinoma. The study found that patients who achieved a >50% decrease in iPTH levels into the normal reference range had a higher rate of operative success compared to those with a >50% decrease […]
Low-Volume Elective Surgery at US Hospital Networks Associated with Inferior Outcomes
Most US hospital networks have low-volume hospitals performing elective surgeries that are associated with inferior outcomes. However, within these networks, there are other hospitals that meet volume standards and are located within a reasonable distance from patients’ homes. The study found significant variation in rates of low-volume surgery across different procedures. Surgical outcomes, including postoperative […]
Textbook Oncologic Outcomes Enhance Survival in CRS and HIPEC for Colorectal Peritoneal Metastasis
Expert consensus was achieved on the definition of textbook oncologic outcomes (TOO) in cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) for colorectal peritoneal metastasis. The consensus criteria included the absence of unplanned re-operations, severe postoperative complications, unplanned readmissions, 90-day postoperative mortality, and contraindications for chemotherapy within 12 weeks. In a cohort of 251 patients, […]
Neoadjuvant Chemotherapy Increases Risk of Postoperative DVT in Distal Pancreatectomy for Pancreatic Adenocarcinoma
Patients with pancreatic adenocarcinoma who undergo distal pancreatectomy and receive neoadjuvant chemotherapy (NAT) are 73% more likely to develop postoperative deep venous thrombosis (DVT) compared to those who undergo upfront resection. This association is significant and highlights the need to prioritize high-risk patients for extended duration prophylaxis. The study analyzed data from 4327 patients using […]
Precision Surgery Shows Promise for Colorectal Liver Metastases with Mutras Tumors
Patients with mutras colorectal liver metastases (crlm) may benefit from anatomic resection (AR) compared to nonanatomic resection (NAR), according to a systematic review and meta-analysis. The study found that AR was associated with a significant improvement in liver-specific disease-free survival and overall disease-free survival among patients with mutras tumors, but not among those with wild-type […]
Delta Radiomic Features Predict Resection Margin and Survival in Pancreatic Cancer after Neoadjuvant Treatment
The study demonstrates that delta radiomic features (DRFs), when combined with clinical variables, are effective in predicting resection margin status (RMS) and overall survival (OS) in neoadjuvant-treated pancreatic cancer patients. The models outperform clinical feature-based and other radiomics feature-based models in predicting OS, disease-free survival (DFS), and RMS. These externally validated, predictive/prognostic DRF models provide […]