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Best Papers in General Surgery
The five that matter, every day.
The study aimed to develop a tool to predict the probability of hypocalcemia after total thyroidectomy (TT) by evaluating the percentage decrease in serum parathyroid hormone (PTH) levels in the first 8 hours postoperatively. They prospectively evaluated 97 TT patients, determining the predictors of hypocalcemia…
Researchers conducted a retrospective analysis using the Modified Frailty Index (MFI) to assess postoperative outcomes in elective hernia repair patients. The study included 14,125 robust patients and 1704 frail patients. Frail patients had higher in-hospital mortality, postoperative morbidity, longer hospital stays, higher healthcare costs, and…
The long-term results of a phase II trial evaluating neoadjuvant gemcitabine, nab-paclitaxel, and S1 treatment in borderline resectable pancreatic cancer with arterial contact (BRPC-A) show promising outcomes. Of the 47 patients, 96% underwent pancreatectomy, and the updated median overall survival was 41.0 months with 2-…
Recurrence rates of ampullary adenomas (AA) after endoscopic papillectomy (EP) were compared between patients with familial adenomatous polyposis (FAP) and sporadic AA. The study included 257 patients from 10 tertiary hospitals. Recurrence occurred in 48% of patients with FAP and 36.9% of patients with sporadic…
In a study evaluating the effect of intraoperative neural monitoring (IONM) during papillary thyroid cancer surgery, researchers found that IONM significantly improved the completeness of thyroidectomy and reduced postoperative levels of stimulated thyroglobulin. Patients who underwent IONM had lower thyroglobulin levels and a higher percentage…
People living with HIV (PLWHIV) and people living with hepatitis C virus (PLWHCV) are less likely to receive emergency general surgical procedures (EGS) than similar patients without these conditions. This is the main result of a study analyzing data from over 500,000 non-elective admissions in…
Robotic limited liver resections (RLLR) resulted in superior perioperative outcomes compared to laparoscopic limited liver resections (LLLR) for posterosuperior liver segments, including reduced open conversion rate, blood loss, and operative time. These benefits were observed in both the overall population and in patients with cirrhosis.…
Multiagent neoadjuvant chemotherapy (NAC) followed by surgery is associated with improved overall survival compared to upfront surgery or single-agent NAC in patients with resectable pancreatic adenocarcinoma. A nationwide study conducted on 5,216 patients found that multiagent NAC led to longer median overall survival (35.8 months)…
This systematic review and meta-analysis of 285 studies, including over 8 million patients, evaluated the procedure-specific risks of symptomatic venous thromboembolism (VTE) and major bleeding in general abdominal, colorectal, upper gastrointestinal, and hepatopancreatobiliary surgeries. The risk of VTE varied widely among procedures, with VTE rates…
The study analyzed data from four randomized controlled trials to determine the significance of primary tumor sidedness (PTS) in early-stage colorectal cancer. The results showed that PTS had no impact on the risk of recurrence in stage II/III colorectal cancer. Treatment stratification based on PTS…
