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Only 20% of patients with caustic refractory benign esophageal strictures (CRBES) were successfully treated with stepwise endoscopic interventions. The success rate was notably higher in those with the recurrent subtype (73%) versus the refractory subtype (0%). A significant 80% of patients eventually required esophageal reconstruction,…
In a trial involving 194 patients facing difficult biliary cannulation, the pancreatic guidewire-assisted fistulotomy method achieved a significantly higher success rate of 93.8%, compared to 81.4% for the transpancreatic biliary sphincterotomy technique (p=0.01). Both techniques exhibited similar rates of adverse events, suggesting that fistulotomy is…
Guidelines developed by the BSG/ACPGBI assist clinicians in managing colorectal polyps for patients with a life expectancy of under 10 years. The guidance outlines 33 recommendations drawn from a consensus process involving 28 experts. It includes assessments of life expectancy, polyp characteristics, and risks of…
In a comparative study of colon adenomas and early-stage cancers, endoscopic mucosal resection (EMR) significantly outperformed traditional surgery. Among 568 EMR patients and 2,054 surgical patients, EMR was associated with a lower all-cause mortality rate (hazard ratio 0.31) and reduced healthcare utilization over an average…
A comprehensive review of 81 studies with 26,251 patients reveals that fully-covered self-expandable metal stents used during endoscopic retrograde cholangiopancreatography result in fewer adverse events compared to plastic stents, though they carry a higher risk of pancreatitis. Plastic stents resulted in more complications and shorter…
A miRNA classifier has been developed to detect occult liver metastasis in pancreatic ductal adenocarcinoma (PDAC), revealing significant deregulation of 34 miRNAs in metastatic cases. This classifier, leveraging three key miRNAs (miR-483-5p, miR-6734-5p, and miR-548q), demonstrated high predictive efficacy in identifying metastasis, outperforming CA125 alone…
A multicenter prospective study aims to evaluate a clinical pathway using routine bedside endoscopy for early detection of anastomotic leakage (AL) following colorectal surgery. Researchers hypothesize that this approach will reduce the median time for AL diagnosis from 15 to 5 days. The pathway includes…
A novel procedure, reversible endoscopic gastroduodenal bypass (REGB), demonstrated 100% technical success in six patients with persistent post-surgical duodenal leaks. Patients experienced significant reductions in drain output and resumed oral intake within three days. Following a mean of 52.6 days, five patients successfully underwent REGB…
A randomized controlled trial involving 69 patients demonstrated that the sequential injection-electrocoagulation method significantly reduced the median time to hemostasis during endoscopic submucosal dissection (17 seconds) compared to traditional electrocoagulation (22 seconds), with p < 0.001. The experimental method also yielded higher visibility scores (3.24…
A cost-effectiveness analysis involving 4,557 patients found that prophylactic clipping (PC) during endoscopic mucosal resection (EMR) of large non-pedunculated colon polyps is beneficial. For a typical 65-year-old undergoing EMR, PC yielded an incremental cost-effectiveness ratio (ICER) of -$154,706. It proved cost-effective for very large polyps…
