A machine learning-based model has been developed to predict postoperative recurrence in patients with duodenal adenocarcinoma, utilizing data from 1,830 patients who underwent radical surgery. Among 100 predictive models tested, the penalized regression + accelerated oblique random survival forest model (pam) delivered the highest performance with a concordance index (c-index) of 0.882 in the training […]
Category: Upper Gastrointestinal Tract
Electroacupuncture significantly reduces postoperative ileus duration.
In a multicenter trial involving 585 patients undergoing laparoscopic gastrectomy for gastric cancer, electroacupuncture (EA) proved effective in reducing postoperative ileus (POI) duration. EA decreased the time to first flatus by over 12 hours compared to sham treatments and standard care, and it shortened the time to first defecation by approximately 15 hours. Additionally, the […]
New tool effectively identifies post-treatment quality of life issues
A six-symptom Lasors tool has been validated for identifying patients suffering from poor health-related quality of life after curative oesophageal cancer treatment. In a cohort of 263 patients, four symptoms—reduced energy, low mood, frequent diarrhea, and bloating—were significantly linked to diminished quality of life. The tool demonstrated strong diagnostic accuracy, with an area under the […]
Nomogram predicts risk of pulmonary infections in surgery patients
A novel nomogram developed by clinicians accurately predicts postoperative pulmonary infections (popis) in esophageal cancer patients. Evaluated across 910 patients, it identified six independent risk factors: age, anemia, neoadjuvant therapy, T stage, thoracic adhesions, and duration of surgery. The model demonstrated strong discrimination with areas under the curve (AUC) of 0.8095, 0.8039, and 0.7174 in […]
High success rate achieved in robotic-assisted esophagectomy
A significant 90% of patients achieved textbook outcomes following robotic-assisted minimally invasive esophagectomy (RAMIE) in a single-center analysis involving 150 consecutive patients. Key findings included a median hospital stay of 7 days, low mortality rates of 0.7% at 30 days and 1.3% at 90 days, and a complete pathologic response in 27% of patients. These […]
Deep learning model enhances safety in laparoscopic gastrectomy
A deep learning-based model was developed for real-time recognition of perigastric blood vessels during laparoscopic radical gastrectomy. In testing, the model demonstrated high precision (mean 0.9442) and recall (mean 0.9099) for arteries and maintained robust performance across various challenging conditions. It showed potential to improve intraoperative safety and reduce the risk of accidental bleeding, particularly […]
New nomogram model accurately predicts survival in gastric cancer patients
A newly developed nomogram model provides effective predictions for overall survival in gastric carcinoma patients. Based on analysis of data from 2018 to 2020, ten independent prognostic factors, including body mass index and TNM stage, were identified. The model demonstrated strong predictive capacity, with AUC values nearing 0.85 for 1-year survival in both training and […]
Enhanced lymph node dissection improves outcomes in gastric adenocarcinoma patients
Findings indicate that lymph node dissection (LND) during upfront gastrectomy significantly impacts prognostic outcomes for gastric adenocarcinoma (GAC) patients. The study recommends total lymph node (TLN) counts of ≥18 for detecting positive nodes and ≥23 for identifying N3 status. Furthermore, a negative lymph node count (NLN) >9 correlates with better survival in N+ GAC patients, […]
High glycemic variability increases risk of postoperative complications.
High glycemic variability on the first postoperative day significantly correlates with increased risk for infection-related complications in gastrointestinal cancer patients undergoing radical surgery. A study of 438 patients identified elevated glycemic levels, high leukocyte counts on the fourth postoperative day, and alcohol consumption as independent risk factors. Utilizing machine learning, researchers developed three effective nomogram […]
Conditional survival improves significantly after gastrectomy for gastric cancer
In a cohort of 1,129 gastric cancer patients undergoing curative gastrectomy, distinct improvements in conditional survival (CS) were observed over 10 years, particularly in stages II and III. The 5-year disease-specific survival rates consistently increased. Notably, survival rates for disease-specific causes intersected for stage II at 7 years and stage III at 8 years. Factors […]