Endoscopic submucosal dissection (ESD) was found to enhance postoperative gastrointestinal function and nutritional status in patients with early gastric cancer (EGC). A study involving eighty patients demonstrated higher resection rates with ESD compared to endoscopic mucosal resection (EMR). Though the ESD group experienced increased operative bleeding and longer surgery times, they enjoyed quicker gastrointestinal recovery. […]
Category: Upper Gastrointestinal Tract
Elevated Lactate Levels Predict Anastomotic Leakage Risk
Elevated postoperative lactate levels significantly predict anastomotic leakage (AL) following minimally invasive esophagectomy, with an occurrence rate of 8.9% among evaluated patients. Analysis revealed that lactate measured on postoperative day 2 serves as a strong independent predictor of AL, showcasing an odds ratio of 11.9. Patients with higher lactate not only experienced severe AL more […]
Stair climbing test predicts postoperative outcomes better than gait speed.
In a study involving 548 gastric cancer patients undergoing radical gastrectomy, stair climbing test (SCT) proved to be a superior predictor of postoperative complications and survival outcomes compared to gait speed test (GST). Low SCT performance correlated significantly with increased complications and longer recovery times, while GST did not show similar predictive validity. Combining SCT […]
Laparoscopic fundoplication enhances esophageal motility in GERD patients
Laparoscopic fundoplication significantly improves esophageal motility in patients with gastroesophageal reflux disease (GERD), irrespective of their initial motility status. A study involving 124 patients found that successful fundoplication was associated with normalization of motility, with 103 achieving good outcomes. All procedures were performed laparoscopically without postoperative mortality in the first 90 days. These findings suggest […]
Modified surgical technique significantly lowers anastomotic leakage rates
A new surgical technique for subtotal esophagectomy effectively reduced anastomotic leakage (AL) rates. Researchers compared outcomes between a conventional group and a modified procedure group. AL decreased from 16.9% to 2.8% (p=0.002), with further analysis showing 14% in the conventional group versus 0% in the test group (p=0.006). Key factors contributing to AL included the […]
Preoperative CT features predict surgical outcomes in gastric tumors
Enhanced lesion size on contrast CT significantly correlates with increased operative duration, extended hospital stays, and higher postoperative antibiotic use. A critical finding highlights the intraoperative perforation rate being markedly higher for tumors exhibiting outgrowth compared to those confined to the lumen (96.88% vs 29.11%, p < 0.001). The study underscores CT's superior accuracy in […]
Vagus nerve preservation reduces postoperative complications in gastric cancer
A randomized clinical trial involving 264 patients with early distal gastric cancer demonstrated that preserving the vagus nerve during laparoscopic distal gastrectomy significantly reduced the incidence of postoperative gastroparesis (0.8% vs. 7.6%) and gallstone formation (0% vs. 6.8%) compared to resection. Quality of life assessments revealed the vagus nerve preservation group experienced fewer nausea, vomiting, […]
Predictive model developed for cachexia in gastric cancer patients
A new prognostic model for cachexia in postoperative gastric cancer patients was developed and validated across two cohorts. Focusing on twelve key factors, the model achieved promising performance with AUC values of 0.805 in the training set and 0.795 in the external validation cohort. Calibration and decision curve analyses confirmed its clinical utility, enabling healthcare […]
H. pylori infection identified as key factor in gastric cancer recurrence
A machine learning study involving 1,234 gastric cancer patients revealed that H. pylori infection is the predominant high-risk factor for cancer recurrence post-gastrectomy. Utilizing four algorithms, the XGBoost model outperformed others in accuracy, identifying critical risk elements such as tumor invasion depth and lymph node metastasis. The findings suggest that machine learning can aid clinicians […]
Risk scoring model effectively predicts peritoneal recurrence in gastric cancer
The study identified key risk factors for peritoneal recurrence (PR) in gastric cancer, involving 622 patients post-gastrectomy. Among these, 64 experienced PR with significantly poorer survival rates compared to those with recurrence in other sites. A newly developed risk-scoring model, based on eight variables, demonstrated 81% accuracy in predicting PR. Notably, 82.8% of patients with […]