An updated meta-analysis involving 11,981 gastric cancer patients revealed that preoperative sarcopenia is linked to substantial postoperative complications, including increased rates of mortality, readmission, and severe complications. Sarcopenic patients exhibited notably higher incidences of pulmonary issues, bowel obstructions, and pancreatic fistulas, leading to significantly poorer overall and disease-free survival rates. These results underscore the critical […]
Category: Upper Gastrointestinal Tract
Minimally invasive surgery reduces complications in gastric cancer treatment
Among 4,429 patients undergoing gastric adenocarcinoma resection (2016-2022), minimally invasive surgery (MIS) was linked to lower complication rates compared to open gastrectomy, with fewer major complications (13.1% vs. 18.5%) and reduced perioperative mortality (0.57% vs. 1.53%). Despite these benefits, MIS utilization remained stagnant, indicating a persistent preference for open surgery. Disparities in treatment access persist, […]
New Techniques Enhance Endoscopic Treatment for Gastric Tumors
Recent advancements in peroral flexible endoscopy improve approaches to managing gastric subepithelial tumors (SETs) with malignant potential. Resection techniques depend on tumor size, with options like endoscopic mucosal resection for superficial lesions and endoscopic enucleation for small tumors. When full-thickness resection is complex, laparoscopic and endoscopic cooperative surgery provides a viable alternative. High caution is […]
Predictive model developed for lymph node metastasis in early gastric cancer
A nomogram created to forecast lymph node metastasis (LNM) in submucosal early gastric cancer (EGC) shows significant predictive accuracy. Analyzing data from 389 patients, the model employs risk factors like gender, CA199 levels, and tumor traits, achieving an area under the curve of 0.82 in training and 0.74 in validation sets. This tool aims to […]
Enhanced recovery protocols improve outcomes after oesophagectomy
A systematic review and meta-analysis of six randomized clinical trials involving 850 patients highlights the benefits of enhanced recovery after surgery (ERAS) protocols following oesophagectomy. The analysis showed significantly reduced overall complication rates, pulmonary complications, and shorter post-operative length of stay and time to flatus in the ERAS group compared to standard care. However, no […]
Effective management strategies for recurrent laryngeal nerve palsy identified
Recurrent laryngeal nerve palsy remains a major complication after minimally invasive esophagectomy for esophageal cancer. Despite advancements, incidence rates have not improved significantly. The review examines prevention strategies such as nerve integrity monitoring and robotic surgery, which show varied effectiveness. Management techniques include voice rehabilitation and surgical options like thyroplasty. A multidisciplinary approach focused on […]
Modified suturing technique achieves high closure rate in duodenal ESD
A modified double-layered suturing method, known as the origami method, demonstrated a 96% success rate in achieving complete closure of large mucosal defects following duodenal endoscopic submucosal dissection (ESD). In a review of 28 cases, closure was completed with a median time of 16 minutes, and no complications such as perforations or bleeding were observed. […]
Key predictors identified for successful outcomes in gastroparesis treatment
A systematic review of 1,899 articles identified 30 relevant studies on gastric peroral endoscopic myotomy (GPOEM) for refractory gastroparesis. Findings revealed a GPOEM response rate of 63.1%. Key predictors for a positive response included older age, shorter gastroparesis duration, nondiabetic etiology, lower body mass index, and previous improvement with intrapyloric botulinum toxin. However, variability in […]
Favorable long-term outcomes observed in gastric neuroendocrine tumors
A study analyzing 69 patients with gastric neuroendocrine tumors (GNETs) showed a favorable prognosis, with 5-year survival rates at 93.8% and recurrence rates at 7.25%. Most tumors were grade 1 and type I, with treatment variations between tumor grades; grade 1 patients often opted for endoscopic treatment, while grade 2 received surgical or chemotherapeutic interventions. […]
Machine learning effectively predicts early recurrence in gastric cancer.
A multicenter study identified early recurrence (ER) within two years post-surgery in 15% of 11,615 gastric cancer patients. Utilizing machine learning, researchers developed a stacking ensemble model that achieved an area under the receiver operating characteristic curve of 1.0 for training and 0.8 for testing, indicating robust predictive capability. Key predictors included tumor size, staging, […]