A retrospective analysis involving 2,163 asymptomatic individuals revealed that small-sized magnetically controlled capsule gastroscopy (mccg) successfully detected gastrointestinal issues such as submucosal tumors (1.57%), polyps (15.16%), and ulcers (1.25%). Detection rates for polyps were notably higher in females and increased with age. The procedure was well-tolerated, with no significant discomfort or adverse events reported, demonstrating […]
Category: Upper Gastrointestinal Tract
Endoscopic submucosal dissection is pivotal for early gastric cancer treatment
Endoscopic submucosal dissection (ESD) is crucial for early gastric cancer (EGC) management, often necessitating additional gastrectomy in cases deemed non-curative. Analysis of 134 patients revealed key factors such as deep submucosal invasion and positive margins that led to further surgical intervention. Notably, independent risk factors for lymph node metastasis included positive vertical margin and lymphatic […]
Bolus exposure predicts postoperative symptom resolution better.
In a retrospective study involving 72 patients, bolus exposure emerged as a superior predictor for postoperative symptom resolution in gastroesophageal reflux disease (GERD) after laparoscopic Nissen fundoplication. It outperformed traditional parameters like acid exposure time and DeMeester score for predicting symptom relief, notably for epigastric pain and regurgitation. Notably, in patients without pathological reflux, bolus […]
Adjuvant chemotherapy improves survival in select gastric cancer patients
Findings reveal that adjuvant chemotherapy significantly enhances overall survival in patients with locally advanced gastric cancer post-neoadjuvant chemotherapy. Specifically, those receiving adjuvant therapy showed a 2-year overall survival rate of 86.2% compared to 64.1% for those who did not (p = 0.002). Critical factors influencing adjuvant treatment inclusion included patient age and ASA grade, while […]
Machine learning model predicts malignant potential of gastric tumors
A novel machine-learning model effectively predicts the malignant potential of gastric gastrointestinal stromal tumors (GISTs), identifying key risk factors such as endoscopic ultrasound features, tumor margin clarity, diameter, and monocyte-to-lymphocyte ratio. Tested with 318 patients, the logistic classification model achieved high performance with area under the curve values of 0.919 and 0.925 for training and […]
Standardized management strategies established for failed fundoplications
An international expert panel formulated 33 statements addressing the definition and management of post-fundoplication symptoms. With over 80% agreement, the consensus focuses on resolving symptoms rather than achieving normal physiology. Key areas addressed include dysphagia, heartburn, and the appropriateness of revisional surgeries, along with necessary investigations for symptomatic patients. This initiative marks the first global […]
EUS-guided gastroenterostomy shows promise over traditional methods
EUS-guided gastroenterostomy has gained recognition as an effective alternative to surgical gastrojejunostomy and duodenal stenting for treating gastric outlet obstruction. Key advantages include reduced invasiveness, shorter hospital stays, and potentially improved patient outcomes. This comprehensive review highlights the evolved techniques and their comparative effectiveness, affirming that EUS-guided gastroenterostomy offers significant benefits without the need for […]
Per-Oral Endoscopic Myotomy (POEM) Offers Critical Guidelines
A clinical practice update presented vital guidance on per-oral endoscopic myotomy (POEM), emphasizing that extensive diagnostic evaluations are essential before treatment. It highlights POEM as the preferred option for type III achalasia, while also supporting laparoscopic Heller myotomy and pneumatic dilation for other types. Antibiotic prophylaxis, post-procedure monitoring for gastroesophageal reflux disease, and individualized discharge […]
Postoperative complications significantly reduce survival in gastric cancer patients
Postoperative complications notably impact overall survival rates in gastric cancer patients. Among a cohort of 236 individuals, those experiencing complications showed a stark decrease in survival—58.1% at three years compared to 82.3% without complications. Delirium was the most common complication observed. Furthermore, non-cancer-related deaths, primarily from pneumonia, were substantially higher in patients with complications. Factors […]
Perioperative chemotherapy significantly improves survival in esophageal cancer patients
A retrospective analysis of over 57,000 patients with stage II to III esophageal cancer revealed that both perioperative chemotherapy and trimodality therapy significantly enhance overall survival compared to definitive chemoradiation therapy (DCRT). Perioperative chemotherapy showed a median overall survival of 66.2 months, while trimodality therapy had a median of 43.9 months. In contrast, patients receiving […]