A nationwide study in Finland found that patients undergoing gastrectomy at university hospitals experience lower short-term and long-term mortality rates compared to those treated at nonuniversity hospitals. An analysis of 10,455 patients from 1987 to 2016 indicated that university hospital patients were younger and had more comorbidities. Notably, survival rates at university hospitals were higher […]
Category: Upper Gastrointestinal Tract
Multimodal prehabilitation enhances recovery in frail gastric cancer patients
Multimodal prehabilitation significantly improved physical capacity and reduced chronic inflammation in frail elderly patients undergoing gastric cancer surgery. The intervention, encompassing physical training, nutritional support, and psychosocial treatment over two weeks, resulted in a mean 6-min walk test change of +28 meters (p < 0.001). Notably, inflammation-related indicators improved, and proinflammatory cytokine release decreased, with […]
Machine learning predicts duodenal stump leakage risk in gastric cancer
A new predictive model utilizing machine learning has shown promise in forecasting duodenal stump leakage after laparoscopic gastrectomy for gastric cancer. Analyzing data from 4,070 patients, the support vector machine emerged as the most effective algorithm, achieving high sensitivity, accuracy, and specificity. Key factors influencing leakage risk include tumor location, tumor stage, operation time, preoperative […]
Fatigue and Alopecia Are Key Challenges in Esophageal Cancer Treatment
In a study of 75 esophageal squamous cell carcinoma patients undergoing neoadjuvant immunochemotherapy, treatment-related adverse events (TRAEs) were better characterized over time using latent-class mixed-modeling. Most TRAEs, including pruritus, nausea, vomiting, and pain, improved, while fatigue and alopecia worsened. Patients with severe gastrointestinal TRAE trajectories had significantly poorer overall survival compared to those with mild […]
High energy intake in postoperative nutrition mitigates complications.
Supplementary parenteral nutrition (h-spn) with higher energy intake decreased postoperative hospital stays and infectious complications among gastric cancer patients. In a study of 128 patients, the h-spn group had an average stay of 8.11 days compared to 10.38 days for the l-spn group and significantly fewer infections, particularly pulmonary. Furthermore, there were no added costs […]
Anterior gastropexy significantly reduces 1-year recurrence of hernia
Findings indicate that incorporating anterior gastropexy during minimally invasive paraesophageal hernia repair significantly lowers the 1-year recurrence rate. In a clinical trial involving 240 participants, the recurrence rate was 15% for those receiving anterior gastropexy compared to 36% for those without it, indicating a notable risk difference. While patient satisfaction and quality-of-life outcomes remained consistent […]
Deep learning model predicts early recurrence in gastric cancer
A deep learning model (DLRMLP) integrating clinical factors outperformed traditional methods in predicting early recurrence of locally advanced gastric cancer (LAGC) post-gastrectomy. In a study involving 620 patients, DLRMLP achieved an AUC of 0.891 compared to 0.797 with conventional models. This model effectively stratified early recurrence-free survival, disease-free survival, and overall survival (all p < […]
Subcomplete sealing technique minimizes recurrent laryngeal nerve palsy
The subcomplete sealing technique significantly mitigated the risk of recurrent laryngeal nerve (RLN) palsy during esophagectomy. Among 76 patients undergoing the procedure, only 3.95% experienced grade IIa RLN palsy, with no cases of more severe injuries. This approach utilizes advanced bipolar energy devices to achieve vessel sealing while preventing thermal injury to nearby nerves, thereby […]
Hybrid Robotic Surgery Enhances Distal Gastrectomy Efficiency
A novel hybrid robotic surgery, integrating minimally invasive laparoscopic techniques with the da Vinci single-port system, demonstrates promise in distal gastrectomy for gastric cancer. This approach allows for a more spacious environment for surgical teams, enhancing their efficiency. The setup permits dual operability—robotic and laparoscopic—facilitating effective nodal dissection with improved surgical quality and reduced operative […]
Adjuvant therapy benefits vary by cancer type in esophageal cancer
A large-scale observational study identified that adjuvant therapy after esophagectomy is beneficial primarily for patients with node-positive squamous cell carcinoma and specific advanced adenocarcinoma stages. Patients with adenocarcinoma experienced survival benefits mainly in cases with PT4 or PTanyN3M0 cancers, while a decrement was noted in less severe cases. For squamous cell carcinoma, survival improvements ranged […]