In a multicenter retrospective study involving 2,189 patients, researchers found that radical surgery significantly improved overall survival rates for duodenal adenocarcinoma, with 1-, 3-, and 5-year survival rates at 91.78%, 69.30%, and 55.86%, respectively. The median overall survival was 73 months. Notably, minimal differences in survival were observed between laparotomy and minimally invasive approaches, though […]
Category: Upper Gastrointestinal Tract
New diagnostic system enhances early gastric cancer detection
An innovative diagnostic system combining color change patterns with vessel classification significantly improved early gastric cancer (EGC) detection. The pink microsurface microvascular (PSV) system outperformed the traditional vessel plus surface (VS) system, achieving 93% accuracy compared to 84.6% for VS. Additionally, the PSV system’s specificity reached 93.4%, surpassing the VS system’s 83.6%. While sensitivity remained […]
Mediastinoscopy-assisted esophagectomy shows shorter operation times and fewer complications
A meta-analysis of 21 studies comparing mediastinoscopy-assisted esophagectomy (MAE) and thoracoscope-assisted esophagectomy (TAE) reveals MAE’s advantages in reducing operation times and intraoperative blood loss, while enhancing postoperative recovery due to fewer pulmonary complications. However, MAE increases the risk of recurrent laryngeal nerve injury and involves fewer lymph nodes dissected. Long-term survival rates remain statistically similar […]
Morbidity and mortality rates are low after antireflux surgery
A study of 2,342 patients undergoing antireflux and hiatal hernia surgery revealed a 30-day morbidity rate of 18.2% and a mortality rate of 0.2%. Most complications were minor, with 13.1% classified as Clavien-Dindo grade less than 3a. In the following 31 to 90 days, morbidity decreased to 3.1% and mortality to 0.09%. Findings indicate that […]
Modified outcomes enhance prognosis for elderly gastric cancer patients
A modified textbook outcome (MTO) was developed for elderly gastric cancer patients, revealing strong correlations between surgical approaches and overall survival (OS). Analysis of 1,389 patients established key factors impacting OS, including MTO, tumor size, pTNM staging, and adjuvant chemotherapy. The nomogram created demonstrated robust predictive accuracy for 1-, 3-, and 5-year OS, with AUC […]
Prehabilitation may improve outcomes for gastric cancer surgery patients
Evidence is being gathered on the potential benefits of prehabilitation for patients undergoing gastric cancer surgery. This systematic review and meta-analysis will investigate the impact of trimodal prehabilitation, including exercise, nutrition, and psychological support, on reducing postoperative complications and enhancing recovery. The study will focus on key outcomes such as complication rates, hospital stay duration, […]
Higher BMI does not worsen outcomes in hernia repair
The study finds no significant correlation between body mass index (BMI) and perioperative outcomes or short-term recurrence after paraesophageal hernia repair in a cohort of 884 patients. Key metrics such as blood loss, length of hospital stay, major complications, and mortality were unaffected by increasing BMI levels. Notably, overweight and obese patients showed no increased […]
Endoscopic full-thickness resection proves effective for tumors
A study analyzing 232 patients undergoing endoscopic full-thickness resection (EFTR) demonstrates its feasibility, safety, and effectiveness for treating upper gastrointestinal submucosal tumors, including predominantly extraluminal lesions. The procedure achieved an en-bloc resection rate of 98.7%, with a negligible recurrence observed over a mean follow-up of 3.7 years. Notably, complications occurred in 9.1% of cases, with […]
Nomograms improve survival prediction in gastric cancer patients
Incorporating a systemic oxidative stress score (soss) based on fibrinogen, albumin, and cholesterol significantly enhances prognostic accuracy for gastric cancer patients post-radical gastrectomy. Among 3,820 patients, nomograms utilizing soss outperformed traditional staging methods in predicting overall and disease-free survival (AUC: 0.830 vs. 0.778, AUC: 0.824 vs. 0.775). Moreover, high-risk groups demonstrated significantly increased recurrence rates, […]
Dysphagia scores significantly impact survival in esophageal cancer patients.
A study involving 302 patients with advanced resectable esophageal cancer revealed that preoperative dysphagia scores are crucial prognostic factors for survival outcomes. Patients with higher dysphagia scores (2-4) exhibited significantly poorer disease-free and overall survival rates compared to those with scores of 0-1. Specifically, 5-year disease-free survival rates decreased from 52.9% to 26.7% as scores […]