Category: Upper Gastrointestinal Tract

Extracapsular spread is a key predictor of early recurrence.

Analysis of 196 patients with oesophagogastric adenocarcinoma revealed a 13.8% early recurrence rate post-surgery, with a one-year recurrence-free survival of 83.7% and overall survival of 90.8%. The study identified extracapsular spread and ypN3 stage as independent risk factors for early recurrence, highlighting their significance in prognostication. Understanding these predictors may guide tailored follow-up strategies, including […]

Standardized measures enhance surgical quality for gastric cancer patients.

The study highlights the importance of measuring surgical quality in multimodal treatment for gastric cancer. By implementing standardized systems for recording complications and ensuring adherence to treatment guidelines, surgeons can optimize patient outcomes. This focus aims to reduce postoperative complications and improve overall quality of life, ultimately influencing long-term oncological results. A composite quality measure […]

Simultaneous robot-assisted esophagectomy reduces surgery time.

A novel approach to robot-assisted cervical esophagectomy combining cervical and abdominal procedures has shown significant advantages. In a study of 30 patients, this simultaneous procedure, utilizing nerve integrity monitoring without muscle relaxants, resulted in a total operative time of 291.2 minutes, markedly shorter than the sequential group’s 453.8 minutes. No intraoperative adverse events or postoperative […]

Endoscopic Vacuum Therapy effectively treats Boerhaave’s syndrome.

A multicenter analysis demonstrates that Endoscopic Vacuum Therapy (EVT) has a high success rate for treating Boerhaave’s syndrome, yielding an 80% treatment success in 25 patients. Mortality rates were significantly lower for EVT patients (8.0%) compared to those undergoing other methods (25.0%). Moreover, treatment success with EVT was statistically superior to non-EVT approaches (43.8%). These […]

Endoscopic submucosal dissection proves more effective than EMR

A systematic review and meta-analysis involving 9,352 patients reveals that endoscopic submucosal dissection (ESD) outperforms endoscopic mucosal resection (EMR) in effectively treating early Barrett’s neoplasia. ESD achieved significantly higher en-bloc resection rates (odds ratio 25.96) but was associated with greater incidence of adverse events. The findings highlight the need for careful consideration of the balance […]

Early esophago-gastric adenocarcinoma linked to high lymph node metastasis risk

A multicenter study involving 1,601 patients revealed a 13.5% incidence of lymph node metastasis (lnm) in early esophago-gastric adenocarcinoma. Factors such as tumor depth and lymphovascular invasion showed initial associations with lnm but lacked significance in multivariable analyses. Notably, surgery following endoscopic resection significantly improved survival rates, highlighting the potential need for reevaluation of predictive […]

Postoperative insulin resistance worsens recovery after gastrectomy.

A cohort study involving 60 gastric cancer patients revealed that postoperative insulin resistance significantly worsens short-term recovery after radical gastrectomy. Key findings indicated increased insulin resistance and inflammation, along with decreased nutritional markers. The gut microbiome showed notable changes, including reduced bifidobacterium and butyrate levels. Negative correlations were found between insulin resistance and beneficial gut […]

High neutrophil-lymphocyte ratio indicates increased mortality risk in UGIB patients

A study involving 726 patients with upper gastrointestinal bleeding (UGIB) revealed that a high neutrophil-lymphocyte ratio (NLR) on admission significantly predicts in-hospital mortality risk. Researchers found that while 6% of patients died, 23.9% required endoscopic intervention, and 46.4% needed blood transfusion. The integration of NLR with the Glasgow-Blatchford Score and Full Rockall Score enhanced risk […]

Endoscopic hand suturing significantly reduces postoperative bleeding risk.

A multicenter phase II study demonstrates that endoscopic hand suturing (EHS) effectively reduces the postoperative bleeding rate to 7% in patients undergoing gastric endoscopic submucosal dissection while on antithrombotic agents. Out of 43 patients analyzed, the EHS method achieved a 100% technical success rate and an 83% closure maintenance rate on day 3 post-operation, with […]