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Upper Gastrointestinal Tract

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World J Surg Oncol5 Mar 2025

Cytoreductive surgery with HIPEC and IORT enhances gastric cancer survival

Findings indicate that cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) and intraoperative radiation therapy (IORT) significantly improves overall survival (63 months) and disease-free survival (87 months) for gastric cancer patients. Over one-third of participants experienced no postoperative complications, while those who did faced a…

Gastroenterology3 Mar 2025

Electroacupuncture significantly reduces postoperative ileus duration.

In a multicenter trial involving 585 patients undergoing laparoscopic gastrectomy for gastric cancer, electroacupuncture (EA) proved effective in reducing postoperative ileus (POI) duration. EA decreased the time to first flatus by over 12 hours compared to sham treatments and standard care, and it shortened the…

Br J Surg3 Mar 2025

New tool effectively identifies post-treatment quality of life issues

A six-symptom Lasors tool has been validated for identifying patients suffering from poor health-related quality of life after curative oesophageal cancer treatment. In a cohort of 263 patients, four symptoms—reduced energy, low mood, frequent diarrhea, and bloating—were significantly linked to diminished quality of life. The…

BMC Surg28 Feb 2025

Nomogram predicts risk of pulmonary infections in surgery patients

A novel nomogram developed by clinicians accurately predicts postoperative pulmonary infections (popis) in esophageal cancer patients. Evaluated across 910 patients, it identified six independent risk factors: age, anemia, neoadjuvant therapy, T stage, thoracic adhesions, and duration of surgery. The model demonstrated strong discrimination with areas…

J Gastrointest Surg27 Feb 2025

High success rate achieved in robotic-assisted esophagectomy

A significant 90% of patients achieved textbook outcomes following robotic-assisted minimally invasive esophagectomy (RAMIE) in a single-center analysis involving 150 consecutive patients. Key findings included a median hospital stay of 7 days, low mortality rates of 0.7% at 30 days and 1.3% at 90 days,…

BJS Open27 Feb 2025

Deep learning model enhances safety in laparoscopic gastrectomy

A deep learning-based model was developed for real-time recognition of perigastric blood vessels during laparoscopic radical gastrectomy. In testing, the model demonstrated high precision (mean 0.9442) and recall (mean 0.9099) for arteries and maintained robust performance across various challenging conditions. It showed potential to improve…

World J Gastrointest Oncol26 Feb 2025

New nomogram model accurately predicts survival in gastric cancer patients

A newly developed nomogram model provides effective predictions for overall survival in gastric carcinoma patients. Based on analysis of data from 2018 to 2020, ten independent prognostic factors, including body mass index and TNM stage, were identified. The model demonstrated strong predictive capacity, with AUC…

Ann Ital Chir26 Feb 2025

Enhanced lymph node dissection improves outcomes in gastric adenocarcinoma patients

Findings indicate that lymph node dissection (LND) during upfront gastrectomy significantly impacts prognostic outcomes for gastric adenocarcinoma (GAC) patients. The study recommends total lymph node (TLN) counts of ≥18 for detecting positive nodes and ≥23 for identifying N3 status. Furthermore, a negative lymph node count…

Medicine (Baltimore)25 Feb 2025

High glycemic variability increases risk of postoperative complications.

High glycemic variability on the first postoperative day significantly correlates with increased risk for infection-related complications in gastrointestinal cancer patients undergoing radical surgery. A study of 438 patients identified elevated glycemic levels, high leukocyte counts on the fourth postoperative day, and alcohol consumption as independent…