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Upper Gastrointestinal Tract

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Ann Surg Oncol5 Jan 2024

Upfront Surgery Valid for cT1-2N1 Esophageal Squamous Cell Carcinoma

The study analyzed the efficacy of neoadjuvant chemoradiation therapy (ncrt) in patients with completely resectable esophageal squamous cell carcinoma (escc) and minimal lymph node involvement (cN1). The researchers conducted a retrospective review of 247 patients who underwent upfront radical esophagectomy followed by adjuvant treatment. They…

Ann Surg Oncol5 Jan 2024

Neoadjuvant Chemotherapy Does Not Increase Postoperative Complications in Gastric Adenocarcinoma

The study compared postoperative complications between neoadjuvant chemotherapy and upfront surgery in gastric adenocarcinoma patients in Finland. Analyzing data from 769 patients, the study found that neoadjuvant chemotherapy did not increase major postoperative complications, including pneumonia, anastomotic complications, wound complications, or other complications. The results…

Surg Endosc4 Jan 2024

International Consensus Defines Quality Measures for Minimally Invasive Gastrectomy

Researchers conducted an international Delphi consensus study to determine expert agreement on the key technical steps of minimally invasive total gastrectomy (MITG) for gastric cancer. A final consensus of 41 statements was reached, outlining crucial steps for performing high-quality MITG for oncological indications. The findings…

Surg Obes Relat Dis4 Jan 2024

Hiatal Hernia Repair Post-Laparoscopic RYGB: Short-Term Symptom Relief

Symptomatic hiatal hernia (HH) with pouch migration is a rare complication after laparoscopic Roux-en-Y gastric bypass (RYGB), and there is limited evidence on the utility of surgical repair. In this retrospective review of 44 patients who underwent isolated HH repair after previous RYGB, researchers found…

Ann Surg Oncol1 Jan 2024

Neoadjuvant Docetaxel-Based Chemotherapy Followed by En Bloc Resection: Effective Treatment for Locally Advanced Esophageal Adenocarcinoma with Comparable Survival Outcomes

Neoadjuvant docetaxel-based chemotherapy followed by en bloc resection is an effective treatment for locally advanced esophageal adenocarcinoma. Results from a 15-year retrospective analysis showed that both docetaxel/cisplatin/5FU and 5FU/leucovorin/oxaliplatin/docetaxel regimens achieved similar survival outcomes. A high percentage of patients completed the neoadjuvant cycles, and the…