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A retrospective study analyzed 182 obese patients who underwent open transversus abdominis release (TAR) for complex ventral hernias. Among these patients, those with a BMI greater than 40 did not show significant differences in surgical site occurrences and infections compared to those with a lower…
This systematic review and meta-analysis compared the use of sterile and nonsterile gloves for wound and laceration repair. The analysis found no significant difference in the rates of infection or wound healing between the two types of gloves. These results suggest that nonsterile gloves are…
Researchers conducted a randomized controlled trial to compare the effectiveness of intraoperative wound irrigation with aqueous povidone-iodine (PVP-I) versus saline in reducing surgical site infections (SSI) in clean-contaminated wounds after gastroenterological surgery. The study included 941 patients and found that the incidence of incisional SSI…
Using telemedicine for remote wound reviews can be upscaled globally and may help reduce the risk of SSI after surgery. In an international cohort study of over 15,000 patients from 66 countries, telemedicine follow-up resulted in slightly lower SSI rates compared to in-person review. This…
Skin wound healing often leads to abnormal scarring, such as keloids or hypertrophic scars, impacting millions globally. While the precise mechanisms remain elusive, evidence suggests ongoing inflammation in susceptible individuals perpetuates extracellular matrix changes, resulting in fibrotic lesions. Abnormal scarring, causing pain, functional impairment, and…
Examining 65,803 emergency laparotomy patients, researchers found no significant difference in surgical site infection (SSI) rates when comparing prophylactic negative pressure wound therapy (NPWT) to standard dressings. Propensity-matched cohorts with completely or partially closed incisions showed similar SSI rates (13.4% vs. 11.9% and 3.6% vs.…
Researchers explore the evolving landscape of mesenchymal stem cell (MSC) therapy in wound healing. While MSCs show promise in tissue repair, their full potential is hindered. The study advocates for combination therapies, citing enhanced efficacy through biomaterials, platelet-rich plasma (PRP), and stress-response manipulation. By synergizing…
Analyzing 19 studies, researchers reviewed whether single-use negative pressure wound therapy (sNPWT) could diminish surgical site infections (SSIs) in at-risk patients with closed surgical incisions. The meta-analysis indicated a significant reduction in composite, superficial, and deep SSIs with sNPWT compared to standard care across diverse…
This mapping review addresses a pressing issue: pain during chronic wound dressing changes. Existing UK guidelines prioritize wound healing over pain management during these procedures. The review aims to gather, assess, and describe current research on strategies for assessing and reducing pain during chronic wound…
