Category: Wounds

Plastic Wound Protectors Significantly Reduce Surgical Site Infections in Open GI Surgery

Researchers found that using a dual-ring plastic wound protector during open gastrointestinal surgery significantly reduced the rate of surgical site infections (SSIs) compared to conventional surgical gauze. In this randomized clinical trial with 457 patients, the SSI rate for the wound protector group was 10.9% versus 20.5% for the gauze group, resulting in a relative […]

Effectiveness of Negative Pressure Wound Therapy in Reducing SSIs after CRS/HIPEC

Researchers found that negative pressure wound therapy (NPWT) can significantly reduce surgical site infections (SSIs) after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). A study of 178 patients showed lower SSI rates with NPWT (5.6%) compared to standard surgical dressing (11.4%). Multivariate analysis confirmed that NPWT was associated with a significantly lower risk of […]

Effectiveness of Hyaluronic Acid/Collagenase Ointment on Chronic Wound Healing

Hybrid ointment significantly improved wound bed scores and reduced healing times across various chronic wounds, with diabetic ulcers showing significant improvement. Patients reported high satisfaction rates, efficient debridement, and pain reduction. This treatment may be a valuable addition to wound care practices, especially for challenging cases like diabetic ulcers. Journal Article by Calavul A in […]

Wound Irrigation in Laparotomy: No Significant Reduction in Surgical Site Infections

Wound irrigation with polyhexanide solution did not significantly decrease the incidence of surgical site infections compared to saline or no irrigation after laparotomies. The study, involving 689 patients, found an overall infection rate of 11.8%, with no statistically significant difference between the groups. Further research is needed to assess the potential benefits in contaminated and […]

Risk factors for anastomotic dehiscence in patients receiving negative pressure wound therapy after intestinal anastomosis.

The use of negative pressure wound therapy (NPWT) during intestinal anastomosis has been controversial. A single-center cohort study was conducted to identify risk factors for anastomotic dehiscence in patients who received NPWT therapy. The study found that females, delayed fascial closure, use of vasopressors, and NPWT pressures >110 mmHg were associated with a higher risk […]

Non-Thermal Plasma accelerates wound healing in abdominal surgeries

Non-Thermal Plasma (NTP) therapy was evaluated as a method to speed up wound healing in patients who underwent laparoscopic and open abdominal surgeries. Researchers used a needle-type reactor with an irradiance of 0.5 w/cm² to apply NTP. The pilot study showed promising results, indicating that NTP therapy can be efficacious and safe in enhancing recovery […]

Customized bacteriophage therapy effectively cures chronic wounds and promotes healing

A randomized, placebo-controlled, double-blind clinical trial evaluated the efficacy and safety of bacteriophage therapy for chronic wounds. Customized bacteriophage cocktails were applied to wounds, resulting in 93.3% becoming sterile in 39 days, followed by complete healing within 90 days. In contrast, 83.3% of wounds treated with placebo remained colonized by bacteria without healing. The study […]

Weight Loss, Not BMI Alone, Predicts Wound Complication Risk in Obese Hernia Patients

A retrospective study analyzed 182 obese patients who underwent open transversus abdominis release (TAR) for complex ventral hernias. Among these patients, those with a BMI greater than 40 did not show significant differences in surgical site occurrences and infections compared to those with a lower BMI. However, patients who achieved at least a 3% preoperative […]

Sterile Gloves Are Not Superior to Nonsterile Gloves for Wound and Laceration Repair

This systematic review and meta-analysis compared the use of sterile and nonsterile gloves for wound and laceration repair. The analysis found no significant difference in the rates of infection or wound healing between the two types of gloves. These results suggest that nonsterile gloves are equally effective in preventing complications during wound and laceration repair, […]

Aqueous Povidone-Iodine Irrigation Does Not Reduce Surgical Site Infection Incidence Compared to Saline Irrigation

Researchers conducted a randomized controlled trial to compare the effectiveness of intraoperative wound irrigation with aqueous povidone-iodine (PVP-I) versus saline in reducing surgical site infections (SSI) in clean-contaminated wounds after gastroenterological surgery. The study included 941 patients and found that the incidence of incisional SSI was slightly higher in the group receiving PVP-I (7.6%) compared […]