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Perspectives, Opinions and Curiosities23 May 2024

Telephone Questionnaire Efficiently Diagnoses Surgical Site Infections in Low-Resource Settings

Telephone questionnaire effectively diagnoses surgical site infections after abdominal surgery in low- and middle-income countries. The questionnaire discriminated between patients with and without infections, displaying high accuracy and consistent performance across different income levels. Cut-off score of ≥4 showed good sensitivity and specificity. Findings suggest…

Appendix, Gallbladder and Surgical Emergencies23 May 2024

Challenges in Caring for Patients with Enterocutaneous Fistulas

Exploring critical care nurses' challenges in managing enterocutaneous fistulas reveals difficulties in nursing care and lack of resources. Collaborative multidisciplinary efforts can enhance patient management, nurse knowledge, and overall outcomes. Improved protocols are essential for quality patient care, focusing on fluid/electrolyte balance, nutrition, sepsis control,…

JAMA Surg3 May 2024

Incisional Wound Irrigation with Antiseptic Solutions Reduces Surgical Site Infections

Researchers found that using antiseptic solutions for prophylactic intraoperative incisional wound irrigation significantly reduced surgical site infections (SSIs). In this systematic review and network meta-analysis involving 41 randomized clinical trials with 17,188 patients, antiseptic solutions showed a 40% relative risk reduction in SSIs compared to…

Ann Surg Oncol3 May 2024

Effectiveness of Negative Pressure Wound Therapy in Reducing SSIs after CRS/HIPEC

Researchers found that negative pressure wound therapy (NPWT) can significantly reduce surgical site infections (SSIs) after cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC). A study of 178 patients showed lower SSI rates with NPWT (5.6%) compared to standard surgical dressing (11.4%). Multivariate analysis confirmed…

Wounds26 Apr 2024

Effectiveness of Hyaluronic Acid/Collagenase Ointment on Chronic Wound Healing

Hybrid ointment significantly improved wound bed scores and reduced healing times across various chronic wounds, with diabetic ulcers showing significant improvement. Patients reported high satisfaction rates, efficient debridement, and pain reduction. This treatment may be a valuable addition to wound care practices, especially for challenging…

JAMA Surg1 Mar 2024

Wound Irrigation in Laparotomy: No Significant Reduction in Surgical Site Infections

Wound irrigation with polyhexanide solution did not significantly decrease the incidence of surgical site infections compared to saline or no irrigation after laparotomies. The study, involving 689 patients, found an overall infection rate of 11.8%, with no statistically significant difference between the groups. Further research…

J Clin Med2 Feb 2024

Non-Thermal Plasma accelerates wound healing in abdominal surgeries

Non-Thermal Plasma (NTP) therapy was evaluated as a method to speed up wound healing in patients who underwent laparoscopic and open abdominal surgeries. Researchers used a needle-type reactor with an irradiance of 0.5 w/cm² to apply NTP. The pilot study showed promising results, indicating that…

Int J Low Extrem Wounds2 Feb 2024

Customized bacteriophage therapy effectively cures chronic wounds and promotes healing

A randomized, placebo-controlled, double-blind clinical trial evaluated the efficacy and safety of bacteriophage therapy for chronic wounds. Customized bacteriophage cocktails were applied to wounds, resulting in 93.3% becoming sterile in 39 days, followed by complete healing within 90 days. In contrast, 83.3% of wounds treated…