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Trisectionectomies Enhance Outcomes in Bismuth Type II-III Cholangiocarcinoma

Trisectionectomies significantly improve survival for patients with localized Bismuth-Corlette type II-III perihilar cholangiocarcinoma.

  • Overall survival improved to 52.4 months with trisectionectomy vs. 31 months for extended hemihepatectomy (p < 0.001).
  • R0 resection rates were higher with trisectionectomies (83.9% vs. 75.8%, p = 0.037).

Consider trisectionectomies for appropriate patients to enhance oncological outcomes without increasing significant morbidity or mortality risks.

  • Grade B-C liver failure occurred more frequently with trisectionectomies (23.4% vs. 11.3%, p = 0.002).

Multicenter Study by Tzedakis S, Dhote A (…) Boudjema K et 23 al. in Ann Surg

Copyright © 2025 Wolters Kluwer Health, Inc. All rights reserved.

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Liver Resection for Colorectal Metastases Sets New Outcomes Benchmark

Liver resection remains a gold standard for colorectal liver metastases, providing critical data for patient selection and surgical outcomes.

  • 90-day mortality rate is under 5% across most groups, signaling low operative risk.
  • One-year overall survival exceeds 85% for most subgroups, but drops to 78% for patients with 10 or more metastases.

Timely assessment of these benchmarks will guide surgical decision-making against emerging alternatives like thermal ablation and transplantation.

  • Five-year overall survival rates are: ≥45% for solitary synchronous, ≥58% for solitary metachronous metastases; ≥28% for more than 3 metastases.

Multicenter Study by Viganò L, Risi L (…) Adam R et 12 al. in Ann Surg

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New model predicts early recurrence risk in pancreatic tumors

Surgeons can now identify non-functioning pancreatic neuroendocrine tumors at high risk for early recurrence preoperatively.

  • Early recurrence occurred in 11% of patients, with a median disease-free survival of 16 months.
  • Neoplastic venous thrombosis predicted a 71% chance of early recurrence; without it, patients with a KI-67 index ≥5% and tumor size ≥3 cm had a 19-41% recurrence risk.

Incorporating this model can enhance surgical decision-making and patient counseling regarding prognosis.

Multicenter Study by Partelli S, Guarneri G (…) Falconi M et 7 al. in Ann Surg

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New AI Model Detects Perineural Invasion in Colorectal Cancer

This machine learning model improves detection of perineural invasion (PNI) in colorectal cancer, crucial for surgical outcomes.

  • LightGBM model achieved an AUC of 0.996 in training, 0.935 in testing, and 0.918 in external validation across 430 samples.
  • PNI correlates with higher T stage, increased lymph node metastasis, and more lymphovascular invasion.

Adopting this model could refine patient selection and enhance prognosis understanding in colorectal surgery.

Journal Article by Pu T, Sun J (…) Ren G et 3 al. in Med Sci Monit

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New model predicts poor outcomes in liver surgery for HCC

Surgeons now have a validated model to identify patients at high risk for early non-curative recurrence after liver resection for hepatocellular carcinoma (HCC), crucial for tailoring postoperative care.

  • Early non-curative recurrence significantly increases overall survival risk (hazard ratio 5.39).
  • Median survival drops from 178.6 months to just 34.7 months in early recurrence cases (p < 0.001).

Implementing this model can refine patient monitoring and improve long-term outcomes after HCC surgery.

  • Key predictive factors include elevated alpha-fetoprotein, larger tumor size, multiple tumors, portal invasion, and serosal invasion.

Journal Article by Shibamoto J, Moriguchi M (…) Sugiura T et 8 al. in Int J Surg

Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc.

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ICG Navigation Outperforms Conventional Technique for Hepatic Hemangioma

Using indocyanine green (ICG) fluorescence navigation in laparoscopic hepatectomy leads to better outcomes for hepatic hemangioma patients.

  • Median blood loss: 100 ml (ICG) vs 200 ml (conventional), p < 0.001.
  • Hospital stays shortened: 5.9 days (ICG) vs 7.1 days (conventional), p < 0.001.

For patients with an Iwate score above 9, ICG significantly reduced operative time (158 min vs 224 min, p < 0.001) and hepatic inflow occlusions.

Consider ICG navigation to enhance surgical precision and patient recovery.

Journal Article by Yu ZN, Li L (…) Zhang M et 7 al. in Surg Endosc

© 2025. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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Liposomal Bupivacaine Beats Ropivacaine for Hemorrhoid Surgery

Liposomal bupivacaine provides superior pain relief compared to ropivacaine for patients post-hemorrhoidectomy.

  • Patients receiving liposomal bupivacaine had consistently lower resting pain scores (median 0-2.0 vs 2.0-4.0, p<0.001).
  • The need for rescue analgesics dropped significantly in the liposomal group (43.9% vs 83.3%, p<0.001).

Consider using liposomal bupivacaine to enhance postoperative comfort and reduce opioid usage.

  • Lower defecation pain scores were also reported (median 3.0 vs 5.0, p<0.001).

Comparative Study by Huang H, Wei S (…) Lu K et 9 al. in BMJ Open

© Author(s) (or their employer(s)) 2025. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ Group.

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Extended thromboprophylaxis cuts VTE rates in colorectal surgery

Extended thromboprophylaxis significantly reduces venous thromboembolism (VTE) risk after colorectal surgery without increasing bleeding complications.

  • VTE rates were reduced to 0.56% with low molecular weight heparin (LMWH) and 0.22% with direct oral anticoagulants (DOAC), compared to no extended treatment.
  • No major bleeding events differed between LMWH and DOAC groups at 90 days.

For high-risk patients, implementing extended thromboprophylaxis for at least 28 days can enhance postoperative outcomes.

Review by Choi JDW, Huynh N (…) Toh JWT et 8 al. in Int J Colorectal Dis

© 2025. Crown.

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Surgical Resection Boosts Survival in HCC After Triple Therapy

Surgical resection significantly improves survival for hepatocellular carcinoma patients who reach complete response following triple therapy.

  • One-, two-, and three-year survival rates post-surgery were 96.0%, 90.8%, and 90.8%, compared to 91.3%, 85.8%, and 73.1% for nonsurgical management.
  • Patients who underwent surgery saw 70.9% achieve pathological complete response; however, the overall complication rate was 24.2%.

Surgical resection should be strongly considered for these patients to enhance outcomes.

Journal Article by Zhang X, Feng X (…) Wang H et 5 al. in Liver Cancer

© 2025 The Author(s). Published by S. Karger AG, Basel.

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Next-gen camera control for cholecystectomy using mixed reality

A new head-mounted mixed reality platform could revolutionize cholecystectomy by improving camera control.

  • Verbal instructions for camera assistants dropped from 15.3 to 0.2 per procedure.
  • Mean operative time decreased from 74.8 to 66.0 minutes.

This technology not only boosts efficiency but also enhances visualization and reliability in surgery.

  • Camera movements were reduced by over 70%, leading to nearly 25% less intraoperative blood loss.

Journal Article by Sun X, Xin J (…) Yi B et 2 al. in J Robot Surg

© 2025. The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature.

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