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Laparoscopic Resection of Liver Segment 4 with Fluorescence Staining: Feasibility and Efficacy

Researchers successfully performed a laparoscopic anatomic resection of liver segment 4 with middle hepatic vein involvement using indocyanine green fluorescence staining. The operation lasted 263 minutes with a 110-minute Pringle maneuver and 400g of estimated blood loss. The patient was discharged on postoperative day 5 without complications, and histopathology confirmed sigmoid carcinoma and R0 margin. This study demonstrates the feasibility and effectiveness of this technique.

Journal Article by Liu Y, Peng Y and Wei Y in Ann Surg Oncol

© 2023. Society of Surgical Oncology.

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Comparison of Robotic-Assisted and Laparoscopic Liver Resection for Liver Malignancies

Robotic-assisted liver resection (RLR) and laparoscopic liver resection (LLR) have similar surgical and oncological outcomes for patients with liver malignancies. A systematic review and meta-analysis of five high-quality cohort studies, involving 986 patients, found no significant differences between RLR and LLR in terms of operation time, conversion to open surgery, complication rates, length of hospital stay, 5-year overall survival, and disease-free survival. Further exploration is needed to determine the specific benefits of RLR for patients with liver malignancies.

Review by Long ZT, Li HJ (…) Zhu Z et 7 al. in Surg Endosc

© 2023. The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.

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EPA for Metastasis Trial 2 (EMT2): Phase 3 Protocol for CRC Liver Metastasis Surgery

The EPA for Metastasis Trial 2 (EMT2) study protocol aims to address the need for safe and cost-effective adjunctive treatment for advanced colorectal cancer (CRC). The trial evaluates the effect of EPA on CRC outcomes in patients undergoing liver resection surgery for CRC liver metastasis. The primary endpoint is CRC progression-free survival, with key secondary endpoints being overall survival, safety, and tolerability of EPA. The study plans to publish full trial results in 2026, with subsequent publications of secondary analyses and translational work.

Journal Article by Hull MA, Ow PL (…) Toogood GJ et 16 al. in BMJ Open

© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY. Published by BMJ.

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Healthcare professionals identify training priorities to manage distress in young people with inflammatory bowel disease and a stoma

Healthcare professionals highlighted the need for training to recognize and manage distress in young people with inflammatory bowel disease (IBD) and a stoma. The study identified 19 training priorities, including addressing stigma, practicalities of stoma management, initiating conversations about distress, considering cultural beliefs, and techniques for assessing patient distress. These findings will inform the development of a training package for healthcare professionals treating young people with IBD and a stoma.

Journal Article by Saunders B, Polidano K (…) Bray L et 5 al. in BMJ Open

© Author(s) (or their employer(s)) 2023. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

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Long-term Survival Outcomes of Liver Resection for Metastatic Anal Squamous Cell Carcinoma

The study evaluated the outcomes of liver resection in patients with metastatic anal squamous cell carcinoma (SCC) to the liver. Among the 21 patients undergoing liver resection and/or ablation, 95% had undergone the Nigro protocol for the primary tumor, with 57% experiencing a complete response. The median overall survival was 32.2 months, and the 5-year overall survival rate was 50%. The most common site of recurrence was the liver. Liver resection can be a beneficial treatment option for carefully selected patients with metastatic anal SCC.

Journal Article by Lo WM, Dogeas E (…) Geller DA et 7 al. in J Surg Oncol

© 2023 Wiley Periodicals LLC.

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Robotic Surgery Proves Promising in Surgical Oncology

Robotic surgery has significantly grown in popularity among general surgeons, including those specializing in surgical oncology. Initially introduced by urologists and gynecologists, this technology has now become a valuable tool in the treatment of various cancers, such as those affecting the gastrointestinal, hepato-pancreatico-biliary, colorectal, endocrine, and soft tissue systems. Although long-term outcomes are yet to be determined, short-term results indicate the potential of robotic surgery in the advancement of cancer treatment.

Review by Hays SB, Corvino G (…) Hogg ME et 5 al. in J Surg Oncol

© 2023 The Authors. Journal of Surgical Oncology published by Wiley Periodicals LLC.

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Multidisciplinary Treatment Guidelines for Hepatocellular Carcinoma in Italy: Surgical Treatments and Expert Collaboration.

The Italian scientific societies involved in hepatocellular carcinoma (HCC) management have collaborated to create updated treatment guidelines using evidence-based methods. This study presents the first part of the guidelines, focusing on the surgical treatments and expert tumor board collaboration for HCC. HCC is the third most common cause of cancer-related death worldwide, and the complexity of its management has increased due to recent advancements. The guidelines aim to provide clinicians with comprehensive recommendations for multidisciplinary HCC treatment in Italy.

Practice Guideline by Cabibbo G, Daniele B (…) Trevisani F et 22 al. in Dig Liver Dis

Copyright © 2023 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

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High-Risk Opioid Prescribing Increases Risk of Persistent Opioid Use in Adolescent and Young Adult Patients

Approximately 5% of adolescents and young adults continue to use opioids after surgery, and this study investigated the impact of postoperative opioid prescribing on persistent use in this population. The study found that high-risk opioid prescribing practices, such as overlapping prescriptions and multiple prescribers, significantly increased the risk of persistent opioid use in this age group. The majority of opioid prescriptions for persistent use were from nonsurgical prescribers. Prescription drug monitoring programs may help identify young patients at risk for long-term opioid use.

Journal Article by Vargas GM, Gunaseelan V (…) Harbaugh CM et 6 al. in Ann Surg

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

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Surgeon supply in US counties has increased from 2010 to 2020

The surgical workforce in US counties was analyzed from 2010 to 2020 in a cross-sectional study. The study reveals that surgeon supply has increased during this period, impacting the accessibility of surgical care. The findings provide important insights for policymakers, healthcare administrators, and clinicians in addressing the distribution of surgeons and improving surgical services in rural and socially vulnerable areas.

Journal Article by Patel VR, Liu M (…) Ibrahim AM et 2 al. in JAMA Surg

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Robotic Enucleation for Challenging Pancreatic Head Insulinomas

The results of this study demonstrate that robotic enucleation is a safe and feasible treatment option for pancreatic head insulinomas located in challenging areas. The use of intraoperative ultrasound and endoscopic retrograde cholangiopancreatography (ERCP) with pancreatic duct stent placement were key components in preserving the pancreatic duct during surgery. Both patients experienced successful resolution of hypoglycemic events postoperatively, indicating the effectiveness of robotic enucleation in treating insulinomas.

Journal Article by Polanco PM, Karalis JD (…) Zeh HJ et 2 al. in Ann Surg Oncol

© 2023. Society of Surgical Oncology.

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