In the quest to understand why some individuals achieve type 2 diabetes (T2D) remission after bariatric surgery while others don’t, a study identified crucial factors. Patients who experienced T2D remission had better β-cell function and higher levels of acyl ghrelin, a hormone. They also had lower visceral fat compared to subcutaneous fat. Additionally, branched-chain amino acids (BCAAs) and VLDL particle size were key metabolic differences. The study suggests that targeting visceral fat and optimizing BCAA metabolism might enhance long-term T2D remission rates post-surgery.
Journal Article by Chaiyasoot K, Sakai NS (…) Batterham RL et 9 al. in Obes Surg
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