Researchers classified intrahepatic cholangiocarcinoma (ICC) into perihilar and peripheral subtypes, revealing distinctive features and survival outcomes. Among 1264 patients, 84.3% were ICC-peripheral, while 15.7% were ICC-perihilar. The perihilar subtype exhibited aggressive characteristics and poorer survival than the peripheral subtype. Interestingly, ICC-perihilar behaved akin to bile duct carcinoma, while ICC-peripheral resembled primary liver malignancies. This novel classification provides crucial insights for tailored treatment strategies and a nuanced understanding of ICC subtypes.
Journal Article by Wei T, Lu J (…) Pawlik TM et 16 al. in Ann Surg Oncol
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