In patients with an elevated risk of postoperative pancreatic fistula after pancreatoduodenectomy, a 10-day course of extended antibiotics significantly reduced the occurrence of clinically relevant fistulas, as well as associated complications like infections and drain placements. Patients on extended antibiotics had a shorter hospital stay compared to those on standard perioperative antibiotics. These findings support the potential benefits of extended antibiotic therapy in mitigating complications and provide a foundation for further investigation.
Journal Article by Ocuin LM, Loftus A (…) Hardacre JM et 5 al. in BMC Surg
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