Subscribe free

Upper Gastrointestinal Tract ·

Neoadjuvant Chemotherapy Takes the Lead in Prolonging Survival for Esophageal Squamous Cell Carcinoma

In the realm of esophageal squamous cell carcinoma (ESCC), the battle between neoadjuvant chemotherapy (NAC) and adjuvant chemotherapy (AC) takes center stage. A squad of 684 ESCC patients engaged in this retrospective face-off at Henan Cancer Hospital. Post Propensity Score Matching (PSM), the NAC squad flexed its muscles, showcasing prolonged overall survival (OS) and disease-free survival (DFS), while reducing total and local recurrence rates. The study concludes: NAC plus surgery emerges as the victorious combo for clinical stage II and III ESCC patients.

Journal Article by Sun HB, Yan S (…) Sun HB et 9 al. in Ann Surg Oncol

© 2023. Society of Surgical Oncology.

read the whole article in Ann Surg Oncol

open it in PubMed

Summaries are written to help you decide what to read. They do not replace the full paper.

Free · 5 minutes a day

Get every new paper in Upper Gastrointestinal Tract.

Plus the Daily Selection: the five most relevant papers of the day, each cut to its key points.

Specialty newsletters: every new paper in your field, as a list of titles linked to the source. Daily Selection: the five that matter, cut to their key points.

FreeNo spamOne-click unsubscribe

More in Upper Gastrointestinal Tract

The latest stitches

Ann Surg Oncol2 Nov 2026

High symptom burden after oesophagectomy

On postoperative day 3, about one in five patients had high symptom burden, and the symptoms most linked to others differed between patient groups.

J Gastrointest Cancer23 Oct 2026

Uniportal esophagectomy linked to fewer pneumonias

In nine comparative studies of minimally invasive esophagectomy for esophageal cancer, uniportal VATS was associated with less pneumonia and a shorter stay than multiportal VATS—but the evidence is not strong enough to establish a preferred approach.

All papers in Upper Gastrointestinal Tract →